Open to opportunities

Xue Cheng

@xuecheng

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Bioinformatics scientist with expertise in genomic data analysis.

United States

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What I'm looking for

I seek a collaborative environment that fosters innovation and growth in bioinformatics research.

I am a dedicated bioinformatics scientist with extensive experience in developing and deploying bioinformatics software solutions. At Genovo Inc, I have successfully developed a multi-panels bioinformatics analysis system and tumor mutation detection software, demonstrating my ability to handle large sequencing data and ensure high-quality results.

My academic background includes a Ph.D. in Bioinformatics from Yat-sen Sun University, where I focused on genomic data analyses. I have published several papers in reputable journals, showcasing my research on population genomics and disease-associated mutations. My work has contributed significantly to the understanding of genetic mechanisms and their implications in health.

Experience

Work history, roles, and key accomplishments

Current

Bioinformatics Scientist II

Current

GENOVO Inc

Apr 2019 - Present (6 years 2 months)

Developed and deployed tumor tissue and ctDNA somatic mutation detection software for a 557-gene panel, utilizing newly developed algorithms for large sequencing data. Successfully analyzed CAP PT test samples with both software, consistently passing CAP PT tests over three years. Designed and performed various analytical performance analyses, including precision studies, analytical sensitivity, t

J2EE Bioinformatics Somatic Mutation Detection Next Generation Sequencing CAP PT Testing Data Analysis Algorithm Development QA Testing

Senior Scientist

MD Anderson Cancer Center

Jul 2017 - Present (7 years 11 months)

Explored the role of AT-hook domain deletion at BRG1 in chromatin remodeling and transcription regulation. Analyzed various RNA-seq and related datasets, including PRO-seq, ATAC-seq, RNA-seq, and ChIP-seq, to investigate regulatory molecular mechanisms.

Molecular Carcinogenesis Seq ChIP Seq Data Analysis Chromatin Remodeling

Postdoctoral Associate

Baylor College of Medicine

Sep 2013 - Present (11 years 9 months)

Carried out genomic data analyses for a population genomic study of rhesus whole sequencing genome, from variant calling to downstream population genomics analysis. Published a paper in Genome Research and contributed to another paper on base-biased evolution of disease-associated mutations in the human genome.

Rhesus Macaque Genome

Scientific Programmer

University of Texas Science Health Center at Houston

Sep 2010 - Present (14 years 9 months)

Conducted research in epidemiological genetics, discovering genetic mechanisms for racial differences in energy expenditure, athletic capability, and obesity. Participated in an NIH-funded project exploring the genetic background of heart diseases, performing data analysis and statistical research.

Genetic Mechanism Discovery Data Analysis Statistics

Associate Professor

Guangdong Institute for Monitoring Laboratory Animals

Sep 2008 - Present (16 years 9 months)

Conducted research on the evolution of duplicate genes, proposing a new model for their preservation in genomes. Constructed the Laboratory Animal Information Network of China as a principal investigator and participated in national projects for laboratory animal selection and toxicity monitoring.

Gene Duplication System Administration

System Administrator

Guangdong Institute for Monitoring Laboratory Animals

Sep 1995 - Present (29 years 9 months)

Constructed the Laboratory Animal Information Network of China as a principal investigator. Participated in the selection of Laboratory Animals for Toxicity Monitoring of Oil Exploration Contaminators and drafted national standards for biological toxicity grading and inspecting methods.

System Administration Principal Investigator Toxicity Monitoring

Education

Degrees, certifications, and relevant coursework

Tarim Agricultural University

B.S., Animal Husbandry

Earned a Bachelor of Science degree in Animal Husbandry. The program provided a comprehensive understanding of animal science, including breeding, nutrition, and health.

Nanjing Agricultural University

M.S., Reproduction and Physiology

Obtained a Master of Science degree in Reproduction and Physiology. The curriculum covered various aspects of reproductive biology and physiological processes.

Sun Yat-Sen University

Ph.D., Bioinformatics

Completed a Ph.D. in Bioinformatics, focusing on advanced computational methods for biological data analysis. Gained expertise in areas such as genomics, proteomics, and systems biology.