Sree krishna Chanumolu
@sreekrishnachanumolu
Bioinformatics scientist building deep-learning genomics pipelines for diagnostics and insights.
What I'm looking for
I’m a bioinformatics scientist who builds end-to-end computational pipelines for genomics and metagenomics, turning raw sequencing data into actionable biological insight. At GeneFront INC., I developed automated metagenomics workflows covering sequence assembly, parallel programming, deep learning, bacterial taxonomy, metabolic network connectivity, motif distribution, and organism abundance estimation.
My work also focuses on genome-scale problem solving for complex samples. I created algorithms for barcode-based de novo genome assembly and haplotyping for diploid and multispecies cases, and I delivered documentation, presentations, and quarterly reporting to support scientific and product decisions.
Before returning to research in the U.S., I served as Founding Director at GeneFront Pharma Pvt. Ltd., executing bioinformatics and computational biology R&D for IVD kit development and diagnostic marker identification. Today, I continue that same mindset in postdoctoral roles—developing deep learning applications for genomic variant selection and probabilistic-graph approaches for interaction atlas discovery.
Experience
Work history, roles, and key accomplishments
Postdoctoral Research Associate
University of Nebraska-Lincoln
Jan 2023 - Present (3 years 5 months)
Developed deep learning methods to select minimal genomic variant sets from low-pass whole-genome sequencing data to predict cattle phenotypes, supporting genotype-to-phenotype modeling.
Bioinformatics Scientist
GeneFront Inc.
Jan 2021 - Jan 2023 (2 years)
Developed an automated metagenomics analysis application using sequence assembly, parallel programming, deep learning, taxonomy, metabolic network connectivity, motif distributions, and organism abundancy estimation; processed 700M sheep reads to estimate ~498 organisms and their abundancies.
Postdoctoral Research Scholar
University of Nebraska-Lincoln
Jan 2016 - Jan 2021 (5 years)
Conducted research on interaction atlases and pathway analysis, including improvements to Bayesian Pathway Analysis, KEGG2Net for pathway-derived gene interaction networks, and FQStat for parallel high-speed FASTQ sequencing quality assessment.
Founding Director
GeneFront Pharma Pvt. Ltd.
Jan 2010 - Jan 2016 (6 years)
Led bioinformatics and computational biology R&D to develop IVD kits, including malarial strain–specific diagnostics for Africa/China/India, dengue envelope-protein diagnostic kits, therapeutic peptide candidates via antibody engineering, and molecular genomic markers for bacterial and viral diagnostic kit development.
Visiting Research Faculty
University of Nebraska at Omaha
Jan 2013 - Jan 2014 (1 year)
Used NGS-based computational methods to identify genes contributing to picrosides (secondary metabolite) production in Picrorhiza kurroa via correlation networks and network pruning approaches.
Education
Degrees, certifications, and relevant coursework
University of Nebraska-Lincoln
Postdoctoral Research Associate, Bioinformatics
2023 -
Postdoctoral Research Associate developing deep learning applications to identify the minimal set of genomic variants in cattle to predict phenotypes from low-pass whole-genome sequencing data.
University of Nebraska-Lincoln
Postdoctoral Research Scholar, Bioinformatics
2016 - 2021
Postdoctoral Research Scholar working on human interaction atlases, Bayesian pathway analysis, KEGG2Net pathway interaction networks, and FQStat sequencing quality assessment.
University of Nebraska at Omaha
Visiting Research Faculty, Bioinformatics
2013 - 2014
Visiting Research Faculty; project used correlation networks and network pruning methods on NGS data to identify genes contributing to medicinal value secondary metabolites (Picrosides) in Picrorhiza kurroa.
Jaypee University of Information Technology
Doctor of Philosophy (PhD) in Bioinformatics, Bioinformatics
2007 - 2013
Earned a Ph.D. in Bioinformatics (2007–2013); thesis focused on computational analysis of bacterial genomes for drug target discovery and understanding the role of SSRS in pathogen evolution.
Jaypee University of Information Technology
Master of Technology (M.Tech.) in Biotechnology (Bioinformatics), Bioinformatics
2006 - 2007
Earned an M.Tech. in Biotechnology with specialization in Bioinformatics (2006–2007); thesis focused on computational analysis of bacterial genomes for drug target discovery.
Jaypee University of Information Technology
Bachelor of Technology in Bioinformatics, Bioinformatics
2002 - 2006
Earned a B.Tech. in Bioinformatics (2002–2006); thesis focused on digital modeling and simulation of glycolysis and TCA cycles.
Availability
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Authorized to work in
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