Krithika Umesh
@krithikaumesh
Bioinformatician specializing in NGS, single-cell RNA‑seq, and reproducible R/Python workflows.
What I'm looking for
I am a bioinformatics professional with hands-on NGS experience in bulk and single-cell RNA‑seq analysis, proficient in R, Python, and reproducible workflows on HPC. I build scalable analysis pipelines, perform differential expression, trajectory and cell–cell communication analyses, and validate methods on large high-dimensional datasets.
I collaborate across interdisciplinary teams on immunology, neurodegeneration, and space-biology projects, and apply machine learning to genomics and clinical datasets. I have curated disease datasets, constructed knowledge maps, and led ML projects for cell classification and healthcare analytics.
Experience
Work history, roles, and key accomplishments
Volunteer Researcher
Brain AWG
Jan 2024 - Present (2 years 2 months)
Performed preliminary bulk RNA-seq analysis of mouse cerebrum and cerebellum under microgravity, producing differential expression summaries and proposing spatial transcriptomics to probe neuroprotective pathways.
Built a scalable single-cell RNA-seq analysis pipeline for public NGS datasets, enabling integrated clustering, differential expression, and pseudotime analyses that identified cell-type biomarkers and trajectories in immunology projects.
Data Curator
Center for Bioinformatics and Computational Biology
Sep 2022 - Jan 2023 (4 months)
Curated AD/ADRD datasets for a deep learning text-mining system, establishing entity relationships across molecular, disease, variant, and gene levels to support downstream AI models.
Patent Analyst
Xlect IP Solutions
May 2011 - Feb 2012 (9 months)
Reviewed and analyzed patent documents to support IP services for clients, contributing to prior-art searches and patentability assessments.
Trainee, IPR
TIFAC
Jun 2010 - May 2011 (11 months)
Completed training in intellectual property rights at the Department of Science & Technology, supporting IP education and policy-related projects.
Education
Degrees, certifications, and relevant coursework
University of Delaware
Master of Science, Bioinformatics & Computational Biology
Activities and societies: Graduate Research Assistant, Gleghorn lab; developed single-cell RNA-seq analysis pipeline and performed pseudotime and differential expression analyses.
Master of Science in Bioinformatics & Computational Biology with research on scalable single-cell RNA-seq pipelines, data integration, and cell-type biomarker identification.
National Law School of India University (NLSIU)
Postgraduate Diploma, Intellectual Property Rights
Activities and societies: Trainee experience in patent analysis and IPR-related roles.
Postgraduate diploma in Intellectual Property Rights and Law.
University of Mysore
Master of Science, Bioscience
Activities and societies: Curated Alzheimer's disease datasets for text-mining and established relationships among molecular and disease entities.
Master of Science in Bioscience focusing on bioinformatics-related data curation and analysis tasks.
University of Mysore
Bachelor of Science, Botany, Biochemistry, Microbiology
Bachelor-level studies in biological sciences covering botany, biochemistry, and microbiology.
Availability
Location
Authorized to work in
Job categories
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