Thomas Cahill
@thomascahill
Postdoctoral bioinformatician delivering reproducible multi-omics insights in disease biology.
What I'm looking for
I’m a Postdoctoral Research Fellow at Queen’s University Belfast, where I conduct multi-omic analyses for Type 2 Diabetes Mellitus by integrating DNA methylation, SNP, and transcriptomic data from large population-based cohorts. I build and apply reproducible bioinformatic pipelines to run differential methylation, pathway enrichment, patient clustering, Cox regression, and advanced statistical modelling to identify biomarkers and mechanistic insights.
Alongside my diabetes work, I analyse snRNA-seq, snATAC-seq, and spatial transcriptomics (STOmics) datasets for Alzheimer’s disease and Down syndrome, including multi-omics integration for obesity-related studies and proteomic biomarker analysis for major depressive disorder treatment resistance. I also contribute to training and research culture through supervision, hands-on coding tutorials, and organising a skills-exchange workshop focused on multi-omic workflows and reproducible analysis practices.
Experience
Work history, roles, and key accomplishments
Bioinformatician
Centre for Genomic Regulation
Aug 2025 - Present (11 months)
Analyze large-scale snRNA-seq, snATAC-seq, and spatial transcriptomics datasets for Alzheimer’s disease and Down syndrome. Build and maintain HPC multi-modal omics pipelines and perform multi-omic integration and biomarker analyses.
Postdoctoral Research Fellow
Queen’s University Belfast
Jun 2025 - Present (1 year 1 month)
Conduct multi-omic analyses on Type 2 Diabetes Mellitus, integrating DNA methylation, SNP, and transcriptomic data from large population-based cohorts. Develop reproducible bioinformatic pipelines and provide secondary supervision and skills workshops.
Post-Doctoral Research Assistant
Queen’s University Belfast
Jan 2023 - Jul 2024 (1 year 6 months)
Supervised undergraduate and postgraduate students through hands-on bioinformatics workshops and guided research projects. Coordinated and led a UKRI grant writing effort and performed advanced bioinformatics work including molecular docking, molecular dynamics simulations, and AI-driven drug candidate library generation.
Lab Demonstrator
Queen’s University Belfast
Jan 2019 - Jun 2023 (4 years 5 months)
Instructed students in core laboratory techniques including rodent dissection, microbiology, aseptic techniques, titrations, spectrophotometry, and pipetting. Led bioinformatics coding tutorials and provided assessment and feedback for coursework and scientific writing and experimental design.
Horizon Project Coordinator
European Union
Oct 2021 - Feb 2022 (4 months)
Assisted in structuring and writing two EU Horizon grant applications and engaged international researchers and industry stakeholders. Oversaw the EU grant portal, produced figures, proofread manuscripts, and ensured compliance with EU regulations.
Education
Degrees, certifications, and relevant coursework
Queen’s University Belfast
PhD in Bioinformatics, Bioinformatics
2019 - 2023
PhD in Bioinformatics focusing on a systems biology approach to dissect the hazardous effects of spaceflight and investigate induced torpor as a therapeutic countermeasure.
Ulster University
MSc in Stratified Medicine, Stratified Medicine
2015 - 2017
MSc in Stratified Medicine with a thesis on FKBP5 as a biomarker for Major Depressive Disorder.
Liverpool John Moores University
BSc (Hons) in Biochemistry, Biochemistry
2012 - 2015
BSc (Hons) in Biochemistry investigating whether ATP affects the methylation status of the miRNA9-1 promoter region.
Availability
Location
Authorized to work in
Job categories
Skills
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