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Thomas CahillTC
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Thomas Cahill

@thomascahill

Postdoctoral bioinformatician delivering reproducible multi-omics insights in disease biology.

United Kingdom
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What I'm looking for

I’m looking for a role where I can build reproducible multi-omics pipelines on HPC, collaborate across biology and computation, and drive biomarker discovery using rigorous statistical modelling—while mentoring others through practical, hands-on methods.

I’m a Postdoctoral Research Fellow at Queen’s University Belfast, where I conduct multi-omic analyses for Type 2 Diabetes Mellitus by integrating DNA methylation, SNP, and transcriptomic data from large population-based cohorts. I build and apply reproducible bioinformatic pipelines to run differential methylation, pathway enrichment, patient clustering, Cox regression, and advanced statistical modelling to identify biomarkers and mechanistic insights.

Alongside my diabetes work, I analyse snRNA-seq, snATAC-seq, and spatial transcriptomics (STOmics) datasets for Alzheimer’s disease and Down syndrome, including multi-omics integration for obesity-related studies and proteomic biomarker analysis for major depressive disorder treatment resistance. I also contribute to training and research culture through supervision, hands-on coding tutorials, and organising a skills-exchange workshop focused on multi-omic workflows and reproducible analysis practices.

Experience

Work history, roles, and key accomplishments

Queen’s University Belfast logoQB
Current

Postdoctoral Research Fellow

Queen’s University Belfast

Jun 2025 - Present (1 year 1 month)

Conduct multi-omic analyses on Type 2 Diabetes Mellitus, integrating DNA methylation, SNP, and transcriptomic data from large population-based cohorts. Develop reproducible bioinformatic pipelines and provide secondary supervision and skills workshops.

Queen’s University Belfast logoQB

Post-Doctoral Research Assistant

Queen’s University Belfast

Jan 2023 - Jul 2024 (1 year 6 months)

Supervised undergraduate and postgraduate students through hands-on bioinformatics workshops and guided research projects. Coordinated and led a UKRI grant writing effort and performed advanced bioinformatics work including molecular docking, molecular dynamics simulations, and AI-driven drug candidate library generation.

Queen’s University Belfast logoQB

Lab Demonstrator

Queen’s University Belfast

Jan 2019 - Jun 2023 (4 years 5 months)

Instructed students in core laboratory techniques including rodent dissection, microbiology, aseptic techniques, titrations, spectrophotometry, and pipetting. Led bioinformatics coding tutorials and provided assessment and feedback for coursework and scientific writing and experimental design.

Education

Degrees, certifications, and relevant coursework

Queen’s University Belfast logoQB

Queen’s University Belfast

PhD in Bioinformatics, Bioinformatics

2019 - 2023

PhD in Bioinformatics focusing on a systems biology approach to dissect the hazardous effects of spaceflight and investigate induced torpor as a therapeutic countermeasure.

Ulster University logoUU

Ulster University

MSc in Stratified Medicine, Stratified Medicine

2015 - 2017

MSc in Stratified Medicine with a thesis on FKBP5 as a biomarker for Major Depressive Disorder.

Liverpool John Moores University logoLU

Liverpool John Moores University

BSc (Hons) in Biochemistry, Biochemistry

2012 - 2015

BSc (Hons) in Biochemistry investigating whether ATP affects the methylation status of the miRNA9-1 promoter region.

Tech stack

Software and tools used professionally

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