At Microcrispr, I design bioinformatics pipelines for CRISPR off-target evaluation and quantify editing efficiency across target sites. I also direct Amplicon sequencing and Hybrid Capture processing and lead computational setup and onboarding for SITE-seq.
At Breast Cancer Now, Institute of Cancer Research (ICR), I developed and deployed HPC pipelines for clinical genomics analysis. I analyzed somatic and germline variants across breast and head and neck cancer studies, and profiled biomarkers including TMB, MSI, CNVs, PAM50, and TNBC subtypes.
I integrated multi-omics data, including Nanostring RNA, 10X Single-Cell transcriptomics, TCR-seq, and methylation datasets. I also applied survival modeling and machine learning to identify prognostic molecular patterns and actionable clinical biomarkers.
Earlier, at the National Genomics Core, CDFD, I built automated WGS pipelines for COVID-19 genomic surveillance and GISAID submissions. My work has also included livestock genotyping and imputation at NDDB, cancer genome analysis at Binstech, and cytogenetic screening at Jaslok Hospital & Research Centre.
