- Work on challenging multi-omics problems
- Collaborate with cross-functional teams (wet lab + dry lab)
- Apply ML/AI to accelerate drug discovery or precision medicine
- Contribute to open-source bioinformatics tools
Aditya Naman Soni
@ansoni10
I'm a bioinformatician, and an upcoming PhD scholar at NTU, Taiwan, specializing in Bioinformatics.
What I'm looking for
I hold 2+ years of research experience in epigenetic dynamic simulation using HMM, Genomics, RNA-Seq analysis, epigenetics, eQTL mapping, and machine learning, Deep learning.
I worked in reputated institutes across CSIR-CCMB, IBAB, and CDFD, I help researchers extract meaningful patterns from complex biological datasets.
WHAT I DO
I build computational pipelines and develop algorithms that:
- Identify disease biomarkers from transcriptomic data (171-sample cohort study)
- Map genotype-phenotype-expression relationships using eQTL analysis
- Predict biological age from epigenetic marks using Random Forest & XGBoost
- Simulate epigenetic dynamics in aging using HMMs and Bayesian inference
RECENT HIGHLIGHTS
1. Published first-author paper in BMC Epigenetics & Chromatin (IF: 4.7)
2. Analyzed 1,796 ENCODE samples for age-associated histone modifications
3. Identified 356 disease resistance genes in crop genome (Panicum miliaceum)
4. Automated RNA-Seq processing pipeline reducing analysis time by 60%
Experience
Work history, roles, and key accomplishments
Junior research fellow
Institute of Bioinformatics and Applied Biotechnology
Aug 2024 - Present (1 year 5 months)
• Working on modelling epigenetic drift to understand the histone modification dynamics during ageing.
• Prepared HMM based algorithm to predict and model the accumulation of noise in replicative aging in
yeast
Project Associate
CSIR-Centre for Cellular & Molecular Biology
Jul 2023 - Jun 2024 (11 months)
• Successfully identified differentially expressed genes, and enriched biological processes using DESeq2
and gsea tools.
• Investigated associations among genotype, gene expression, and phenotype using quantitative traits
analysis, SNP-phenotype, and SNP-gene expression association tests using MatrixQTL and PLINK tools.
• Auto-scripts to process and analyse RNA-Seq and genomic data of 171 samples.
Project Trainee
Centre for DNA Fingerprinting and Diagnosis
Jan 2023 - Apr 2024 (1 year 3 months)
Conducted a genome-wide identification and characterization of NLR proteins in Panicum Miliaceum. Performed sequence similarity analysis and domain classification, revealing patterns among different classes of genes.
Academic Project
Bharati Vidyapeeth Deemed to be University
Jan 2022 - Jan 2023 (1 year)
Performed molecular docking and pharmacodynamic studies to identify potential inhibitors of GbpC formation by Streptococcus mutans. Analyzed ligand-protein interactions and prepared a manuscript for publication.
Intern
Interactive Research School for Health Affairs
Jul 2022 - Aug 2022 (1 month)
Conducted a 28-day subacute oral toxicity study of Cisplatin in mice. Evaluated effects across different doses and monitored body weights, food consumption, and conducted biochemical assessments.
Education
Degrees, certifications, and relevant coursework
Bharati Vidyapeeth
Master of science, Biotechnology
Grade: 9.19
Activities and societies: Published: Molecular Docking and Pharmacodynamic Study of Potential Inhibitors of Streptococcus mutans Biofilm
Thesis:"Genome-wide identification and characterization of NLR genes in Panicum Miliaceum"
Tech stack
Software and tools used professionally
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