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Sam Rymer

@samrymer

Clinical AI Strategy Director at Optum, bringing AI tools into production and growing SaaS pharmacy network revenue by 633%.

United States

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At Optum, I serve as Director of Clinical AI Strategy, Products and Partnerships, guiding AI and machine-learning workflow tools through the AI Review Board and into production. As Product Owner of a SaaS pharmacy platform, I drove a 633% increase in network revenue growth.

Previously at Optum, I directed capital strategy for a $500M annual budget and established a Benefits Realization Process that generated $1.5B in measurable benefits. I also established and led the PMO, delivering the company’s largest product upgrade on time and under budget.

Outside my Optum roles, I’m designing and building AI-powered web and mobile applications with Anthropic’s Claude API, including conversational interfaces and document-generation workflows. I’m also the founder and president of Sonoran Hotdog Society, a nonprofit focused on food security.

Experience

Work history, roles, and key accomplishments

Current

Director of Clinical AI Strategy, Products and Partnerships

Current

Optum

Aug 2023 - Present (3 years 2 months)

Serve as AI chair for the department, leading partnership innovation with IT and implementation of workflow-enhancement AI and ML tools. Drove a 633% increase in network revenue growth as Product Owner of a SaaS pharmacy platform.

AI Strategy Machine Learning Product Ownership Go To Market Strategy Agile Stakeholder Management clinical workflows SaaS

Director, Optum Rx Capital Strategy

Optum

Jan 2021 - Aug 2023 (2 years 7 months)

Directed capital process management for Optum Rx, overseeing a $500M annual budget. Established a Benefits Realization Process that resulted in $1.5B in measurable benefits.

Capital Management Budgeting Benefits Realization Risk Management Financial Analysis Cross functional Leadership

Senior Capital Portfolio Manager

Optum

Mar 2015 - Jan 2021 (5 years 10 months)

Managed a diverse portfolio of strategic initiatives to improve operational efficiency, product development, and go-to-market strategy across Optum Rx. Led high-priority capital projects and managed the analytics team for executive financial reporting.

Portfolio Management Capital Projects Financial Reporting Analytics Resource Allocation Strategic Planning

Senior Portfolio Manager

Optum

Jun 2012 - Mar 2015 (2 years 9 months)

Designed and implemented a new portfolio management process for CatamaranRx (now part of Optum), improving operational performance, financial outcomes, and M&A integrations. Delivered strategic leadership in driving operational excellence.

Portfolio Management Process Improvement M&A Integration Operational Excellence Strategic Leadership

Director, Project Management Office (PMO)

Optum

Sep 2009 - Jun 2012 (2 years 9 months)

Established and led the PMO, driving successful execution of enterprise-level initiatives, including the company's largest product upgrade, delivered on time and under budget. Managed cross-functional teams and ensured adherence to project management standards.

PMO Project Management Enterprise Level Initiatives Cross functional Leadership Budget Management

Global IT Project and Process Manager

Prologis

Apr 2006 - Aug 2009 (3 years 4 months)

Led global IT projects and business process improvement initiatives for Fortune 500 clients, ensuring alignment with business goals. Drove successful project outcomes by managing cross-functional teams and providing progress updates to senior leadership.

IT Project Management Business Process Improvement Cross Functional Team Management Stakeholder Communication

Western U.S. Regional Sales Manager

Humalfa

Jul 2005 - Feb 2006 (7 months)

Managed regional sales teams and client relationships, achieving top-tier revenue growth and driving operational performance across all market segments.

Sales Management Client Relationships Revenue Growth operational performance

Project Manager / Developer

Kaiser Permanente

Jan 2003 - Jul 2005 (2 years 6 months)

Managed clinical research projects, collaborating across departments to meet research objectives, manage timelines, and ensure operational efficiency.

Project Management Clinical Research Cross Department Collaboration Timeline management