Masonny Chen

Spearheaded large-scale clinical and biobank database management (Labmatrix, PowerChart) to support translational oncology research and real-world evidence generation. Collaborated with oncologists, geneticists, and data scientists to design and execute retrospective cohort studies using de-identified patient records. Integrated high-dimensional clinical datasets to develop predictive models using

Directed single-cell sequencing projects using BD Rhapsody to detect circulating DNA and tumor cells in CSF from brain cancer patients. Contributed to the establishment of 10x Genomics Xenium and Visium platforms for spatial transcriptomics and integrated multi-omics data for spatial tumour profiling. Developed analysis pipelines for single-cell RNA-seq and spatial transcriptomics data using R, Se

Led three collaborative research projects with national and international academic and clinical institutions, resulting in four publications. Discovered a novel targeted combination therapy for high-risk neuroblastoma through high-throughput drug screening and co-developed an AAV-based gene therapy. Drafted and obtained multiple animal and human ethics approvals, while supervising junior researche

Coordinated and facilitated the execution of clinical trials aimed at evaluating protein biomarkers for early prostate cancer diagnosis. Assisted in the development and maintenance of study protocols, ensuring compliance with regulatory standards and ethical guidelines. Managed participant recruitment processes, including screening, enrolment, and obtaining informed consent, and contributed to the

Conducted advanced research in pediatric oncology, focusing on translational biology and data-driven approaches. Specialized in integrating genomics, transcriptomics, and health outcomes to inform evidence-based care.

Focused on molecular genomics, gaining expertise in advanced molecular biology techniques and genomic analysis. Developed a strong foundation in the study of genes and their functions at a molecular level.

Studied biomedicine, covering fundamental principles of human biology, disease mechanisms, and therapeutic interventions. Acquired a comprehensive understanding of biological and medical sciences.