Kirk Brote
@kirkbrote
AI-driven product and design leader scaling enterprise and precision medicine platforms.
What I'm looking for
I’ve built product strategy and design orgs from the ground up, then shipped AI-enabled experiences for regulated health and consumer audiences. I led work spanning biomedical platforms with massive data scale and consumer launches like Delta Air Lines and the U.S. Olympic Committee.
Through Kirk Brote Consulting, I founded and scaled a product and design consultancy serving 89 clients across AI/ML, precision medicine, pharma, financial services, and enterprise SaaS. I also co-founded Notenda and guided Exact Sciences product strategy work tied to commercialization outcomes.
In full-time executive roles, I turned around Syapse’s product management organization—owning product P&L across multiple products while leading a 30+ person multidisciplinary team. I led product experience for genomic research and clinical platforms that contributed to 5,000+ rare disease diagnoses.
More recently, I’ve been running 0-to-1 product and design for an AI-powered pharmaceutical MLR compliance platform at VuuAI. I designed agentic AI workflows and a four-state AI verification model that became a foundational interface pattern across the review experience.
Experience
Work history, roles, and key accomplishments
Fractional SVP Product Experience
VuuAI
Jun 2025 - Present (1 year 2 months)
Defined product vision and experience strategy for an AI-powered pharmaceutical MLR compliance platform, running product management and design for a 0-to-1 effort.
Founder & Principal Consultant
Kirk Brote Consulting
Jan 2013 - Present (13 years 7 months)
Founded and scaled an independent product and design consultancy serving 89 clients across 12 verticals, including AI/ML platforms, precision medicine, pharma, financial services, and enterprise SaaS.
UX Architect
Church Pension Group
Jan 2021 - Jan 2025 (4 years)
Designed TCSM, an enterprise benefits administration platform replacing a phone, fax, and paper-forms system for 45,000–50,000 Episcopal clergy and staff.
Vice President, Product Management
Syapse
Jan 2019 - Mar 2020 (1 year 2 months)
Owned the product P&L for the Syapse Insights, Syapse Executive, and Syapse Oncology product suite, growing revenue from $3.75M to $6.8M (+81%) against a $4.5M team budget.
Senior Director, Product Experience
Genuity Science
Mar 2016 - Dec 2018 (2 years 9 months)
Led product experience for genomic research and clinical platforms supporting rare disease diagnosis and population genomics across the US, UK, and Ireland.
Director, UX & Design
CashStar
Sep 2011 - May 2013 (1 year 8 months)
Directed product management and design through 792% company growth and the company's eventual $175M acquisition.
Lead Interaction Designer
Digitas
Jun 2010 - Jul 2011 (1 year 1 month)
Designed the primary digital gateway (search, booking, status, SkyMiles flows) for Delta Air Lines, achieving a 37% improvement in flight-search conversion.
Principal UX Design Lead
Newmarket International
Jan 1997 - Jan 2010 (13 years)
Designed Newmarket's enterprise desktop, web, and mobile applications after a 13-year progression from trainer to principal UX design lead.
Experience Architect
VML
Experience Architect for the original unified framework spanning 40+ U.S. Olympic and Paralympic sport properties.
Mobile Transformation Advisor
Mobiquity
Led a Novartis Rx-to-OTC switch engagement spanning packaging, eInk label investigation, FDA-compliant label and instruction testing, consumer website, and CRM email programs.
Education
Degrees, certifications, and relevant coursework
University of New Hampshire
Bachelor of Arts, Political Science
Activities and societies: Ronald E. McNair Scholar
Bachelor of Arts in Political Science. Ronald E. McNair Scholar.
Availability
Location
Authorized to work in
Website
kirkbrote.comJob categories
Skills
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