GCGérald Coulis
@graldcoulis
Dynamic immunologist with expertise in immune cell-based functional assays.
United StatesWhat I'm looking for
I am a dedicated immunologist with over 5 years of academic experience, specializing in immune cell-based functional assays. My work at the UCI Institute for Immunology has allowed me to investigate the role of regulatory T cells in muscular dystrophy, providing critical insights into T cell differentiation during muscle inflammation. I have collaborated with cross-functional teams to elucidate muscle macrophage functions and their impact on immune responses, spearheading the immunophenotyping of immune cell markers essential for high-dimensional flow cytometry analysis.
Throughout my career, I have developed a strong foundation in both in vitro and ex vivo assay development, with hands-on experience working with human cell lines and tissue cell isolation. My research has contributed to a deeper understanding of autoimmune mechanisms and potential therapeutic targets for cardiac diseases. I am passionate about drug discovery and eager to learn and apply new technologies, aiming to contribute to innovative research and product development in the field of immunology.
Experience
Work history, roles, and key accomplishments
Project Scientist
UCI Institute for Immunology
Apr 2021 - Oct 2024 (3 years 6 months)
Investigated the role of regulatory T cells in muscular dystrophy, providing insights into T cell differentiation during muscle inflammation. Collaborated with cross-functional teams to elucidate muscle macrophage functions and their impact on immune responses in muscular dystrophy.
Postdoctoral Scholar
UCI Institute for Immunology
Mar 2018 - Apr 2021 (3 years 1 month)
Explored the induction and tolerization of dystrophin, focusing on Tregs' potential in suppressing immune responses. Developed a novel preclinical model of dystrophin immunity, enhancing understanding of autoimmune mechanisms in muscle tissue.
Postdoctoral Scholar
SUNY Polytechnic Institute
Nov 2017 - Jan 2018 (2 months)
Investigated the role of PTP1B in cardiac hypertrophy, utilizing in vivo and in vitro tools to decipher the gene silencing complex in cardiac remodeling.
Lecturer
The University of Martinique
Mar 2017 - Jun 2017 (3 months)
Delivered courses in biology and immunology, enhancing pedagogical approaches that fostered scientific inquiry and collaboration among students.
Research Associate
Montreal Heart Institute
Apr 2013 - Mar 2016 (2 years 11 months)
Conducted research on PTP1B, focusing on its role in regulating gene silencing pathways in cardiac hypertrophy, contributing to understanding therapeutic targets for cardiac diseases.
Postdoctoral Researcher
National Research Council (CNR)
Jan 2008 - Oct 2011 (3 years 9 months)
Conducted research on myospryn in cardiac and skeletal muscle pathophysiology, contributing to the understanding of mechanisms relevant to the development of next-generation therapeutics.
Study Engineer
French National Institute for Agricultural Research
Jan 2008 - Oct 2008 (9 months)
Designed and executed cloning strategies and protein purification protocols, contributing to the establishment of a protein library that supports innovative research and product development.
Graduate Student Researcher
University of Clermont-Ferrand
Jan 2004 - Jan 2008 (4 years)
Investigated calpain interactions in muscle function, employing in vitro methodologies to generate data critical for understanding muscle dynamics and potential therapeutic targets.
Master Student Researcher
University of Sorbonne
Dec 2000 - Nov 2003 (2 years 11 months)
Conducted research on calpain's interactions with the contractile apparatus, enhancing foundational knowledge that informs future product development in muscle biology.
Education
Degrees, certifications, and relevant coursework
University of Clermont-Ferrand
Ph.D., Biochemistry and Molecular Biology
2004 - 2007
Investigated calpain interactions in muscle function, employing in vitro methodologies to generate data critical for understanding muscle dynamics and potential therapeutic targets.
University of Sorbonne
Master of Science, Biochemistry and Molecular Biology
2000 - 2003
Conducted research on calpain's interactions with the contractile apparatus, enhancing foundational knowledge that informs future product development in muscle biology.
Tech stack
Software and tools used professionally
Availability
Location
United StatesAuthorized to work in
Job categories
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