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Robert Griffin

@robertgriffin

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Experienced protein biochemist specialising in protein purification and structural biology for drug discovery.

China

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What I'm looking for

I am seeking lab-based roles in protein biochemistry or structural biology within collaborative drug-discovery teams, emphasizing hands-on purification, characterisation, and career growth.

I am an experienced protein biochemist and research scientist with a strong background in protein purification, structural biology and drug-discovery projects. Over a career spanning roles at UCB Pharma, GlaxoSmithKline, Replizyme and Smith & Nephew, I have specialised in AKTA-based purifications, protein characterisation and preparing samples for structural techniques.

I hold an MSc in Structural Molecular Biology (Distinction) and a BSc (Hons) in Biochemistry, and I have applied molecular biology and biochemical techniques across enzyme assay development, monoclonal antibody process development, and target-focused screening projects. I routinely use chromatography, electrophoresis, mass spectrometry and NMR/crystallography sample preparation in lab-based discovery settings.

I am a collaborative team member who presents results at project and departmental meetings, keeps rigorous laboratory records, and brings hands-on experience across expression systems (E. coli and mammalian), biophysical characterisation and mass spectrometry to roles focused on discovering therapeutics for immune and central nervous system diseases.

Experience

Work history, roles, and key accomplishments

Research Scientist

UCB Pharma

Jul 2005 - Apr 2023 (17 years 9 months)

Performed lab-based protein biochemistry and purification to support drug discovery projects for immune and central nervous system diseases, contributing to multiple project teams and supporting structural biology efforts.

AKTA FPLC Affinity Chromatography SEC Protein Expression

Scientist

GlaxoSmithKline

Jan 2005 - Jun 2005 (5 months)

Developed techniques to study protein phosphorylation and supported routine mass spectrometry and protein sequencing workflows for research projects.

Protein Phosphorylation Protein Sequencing Molecular Biology Data Analysis

Process Scientist

GlaxoSmithKline

Jun 2004 - Aug 2004 (2 months)

Conducted small-scale purification of monoclonal antibodies for process development using AKTA systems and various chromatography modalities.

Monoclonal Antibody Purification AKTA Prime Process Development

Scientist

Replizyme Ltd

Oct 2002 - Jan 2004 (1 year 3 months)

Worked on enzyme assay development and produced mammalian DNA polymerases in E. coli to support drug screening and counter-screening against polymerase targets.

Protein Expression E. Coli Expression Biochemistry Assay Screening

Protein Biochemist

Smith & Nephew

Feb 2002 - Oct 2002 (8 months)

Developed and tested protein-based wound-healing gel prototypes, performing protein quantification assays (BCA, collagen assays, ELISAs) to support product development.

Protein Quantification Collagen Assays Product Development