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James CapecciJC
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James Capecci

@jamescapecci

I build bioinformatics tools for protein engineering and sequence-data workflows.

United States
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I'm building bioinformatics tools for protein engineering and sequence analysis while pursuing an M.S. in Bioinformatics at Loyola University Chicago.

As a Bioinformatics Intern in the Dr. Kekenes-Huskey Lab at Stritch School of Medicine, I developed PyRosetta tools and a simulated annealing optimizer to engineer LQHIII variants for cardiac-like NaV1.5 binding.

I evaluated 160 variants using interaction distances and predicted ΔG to identify favorable candidates. My projects also include AEGIS, a command-line machine learning pipeline that predicts mutational hotspots in viral protein sequences from NCBI data.

I've developed reproducible Python CLI tools for FASTA processing, evaluated machine learning models for stroke prediction, and taught biology, genetics, and laboratory techniques as a General Biology TA.

Experience

Work history, roles, and key accomplishments

CR

Server Assistant

Cooper's Hawk Winery & Restaurant

Jun 2025 - Aug 2025 (2 months)

Delivered food efficiently while maintaining clean, organized service areas. Managed multiple tasks in a fast-paced environment.

Education

Degrees, certifications, and relevant coursework

Loyola University Chicago logoLC

Loyola University Chicago

Master of Science, Bioinformatics

Grade: 3.73/4.0

Pursuing a Master of Science in Bioinformatics with an expected graduation in May 2027.

Illinois Wesleyan University logoIU

Illinois Wesleyan University

Bachelor of Science, Biology

Grade: 3.80/4.0

Graduated with a Bachelor of Science in Biology, Magna cum Laude, in May 2025.

Illinois Wesleyan University logoIU

Illinois Wesleyan University

Certificate, Data Analytics

Completed a Data Analytics Certificate.

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