Technologist

Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.

Did you know that we are the 1st biologics contract manufacturer in Singapore? We offer you exposure to upcoming biotech and established pharmaceutical companies and to the manufacturing technology needed to produce mammalian treatments and cell therapies of tomorrow. Our global manufacturing network is recognized for its reliable, high-quality services, regulatory track record, global footprint, innovative technology platforms and extensive experience – we, in Singapore are proud to be part of this global network.

The successful applicant for this position will be joining the Analytical Development team within Clinical Development in Lonza Singapore. The Clinical Development group is responsible for the development and characterization of manufacturing processes used for the production of novel therapeutic recombinant proteins for Lonza’s global client base. The purpose of this role is to execute laboratory work to generate analytical data to support the cell line development and upstream/downstream process development teams.

Duties and Responsibilities include:

• Support process development teams by generating analytical test data to enable cell line selection, upstream process development and purification process development.

• Note: A subset of analytical activities are performed to cGMP standards and may suit a candidate with experience in a QC laboratory.

• Test methods include:

• HPLC methods: size exclusion HPLC, Protein A HPLC, RP HPLC, oligosaccharide analysis.

• Capillary based methods: CE SDS, icIEF.

• ELISA methods: antigen binding assays, host cell protein determination, detection of residual Protein A.

• Other methods include qPCR testing for residual DNA, titer determination using Octet and western blotting.

• Collaborate with other functions within the department, to enable smooth progress of projects.

• To communicate project updates to internal stakeholders.

• To contribute to the efficient running of the department including instigating and delivering operational efficiency projects.

• To work to the highest scientific standards under the direction of the Line Manager.

• Contribute to departmental safety programs.

• The role may require weekend working on an ad hoc basis.

• Meticulous and attention to detail.

​

Education / Experience

• Up to 2 years practical laboratory experience in analytical testing would be considered advantageous although full training will be provided for entry level candidates.

• Theoretical knowledge of mammalian protein expression and protein biochemistry.

• Familiarity with Microsoft Office and other relevant software packages.

• Demonstrated experience of direct interaction with external and/or internal customers would be considered beneficial.

• Good problem solving and analytical skills.

• Good communication skills (verbal and written)

• Good team working skills.

• Good understanding and application of cGMP concepts.

Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.