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Vedant Kulkarni

@vedantkulkarni2

Computational biology researcher at Barabási Lab building drug-target prediction pipelines and modeling protein-ligand interactions.

United States
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At Topo Therapeutics, Inc., I analyze cryoEM single-particle data to detect and quantify ligand-induced changes in target proteins. I also develop automated tools for cryoEM processing, modeling, and conformational change prediction in support of preclinical drug discovery.

At Barabási Lab, I contribute to AI-Bind 2, a graph neural network framework for drug-target interaction prediction. I built a Bash pipeline that retrieves structures from PDB and compounds from PubChem, runs docking simulations, and extracts binding affinity scores to help validate model predictions.

At Northeastern University, I supported students in RNA-seq analysis, differential expression workflows, and Python/R programming as a Teaching Assistant for Transcriptomics. I developed coding tutorials and pipeline documentation, and provided debugging support.

At Sahyadri Post Harvest Care Ltd, I designed Python pipelines to extract, clean, curate, and quality-check data, processing more than 2,000 monthly data points. I also established Git-based version control and documentation standards for a five-person team, improving reproducibility by 25%.

Experience

Work history, roles, and key accomplishments

NU

Teaching Assistant – Transcriptomics

Northeastern University

Jan 2026 - Apr 2026 (3 months)

Supported 25 students in RNA-seq data analysis, differential expression workflows, and Python/R programming. Developed coding tutorials and pipeline documentation, and conducted weekly office hours and one-on-one debugging support.

Education

Degrees, certifications, and relevant coursework

Northeastern University logoNU

Northeastern University

Master of Science, Bioinformatics

2025 -

Grade: 3.9/4.0

Activities and societies: Coursework: Computational Biology, Genomics, Transcriptomics, Biostatistics, Machine Learning, Data Science.

Pursuing a Master of Science in Bioinformatics with a GPA of 3.9/4.0, expected to graduate in April 2027.

KB

K.K. Wagh College of Agril. Biotechnology

Bachelor of Technology, Biotechnology

2019 - 2024

Grade: Top 3% of Class

Earned a Bachelor of Technology in Biotechnology with honors, ranking in the top 3% of the class.

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