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Shiva Nickaria

@shivanickaria

Translational immuno-oncology scientist at ARIA Therapeutics building an AI/ML drug development platform for oncology and genetic diseases.

United Kingdom
Message

At ARIA Therapeutics, I’m building an AI/ML-driven drug development platform for oncology and genetic diseases, integrating multi-omics data to prioritise therapeutic targets and optimise candidates.

At the University of Manchester, I developed a machine-learning and image-analysis pipeline for high-plex CODEX imaging. I used spatial proteomics and single-cell RNA sequencing to study tumour–immune interactions and identify predictive biomarkers.

During my PhD at the University of Aberdeen, I engineered an antibody-based immunotherapy for B-cell haematological malignancies and assessed its efficacy and safety in preclinical models. I also developed GMP-grade production protocols and IND-enabling applications.

Earlier, at Nemazee Hospital and SN.Aryan for Advanced Diagnosis and Therapy, I worked across genome editing, clinical genetics, and precision diagnostics. I’ve founded ventures, secured research funding, and mentored students and junior scientists.

Experience

Work history, roles, and key accomplishments

University of Oxford logoUO

Fellowship in Genome Editing

University of Oxford

Oct 2018 - Jan 2019 (3 months)

Conducted genome editing in haematopoietic stem cell lines using base editing for treatment of anaemia.

Education

Degrees, certifications, and relevant coursework

University of Aberdeen logoUA

University of Aberdeen

PhD, Medical Sciences

2019 - 2024

PhD in Medical Sciences with a focus on immuno-oncology and cancer immunotherapy, including the engineering of antibody-based immunotherapies and in vivo validation.

University of Shiraz logoUS

University of Shiraz

MSc, Cellular and Molecular Biology

2011 - 2013

MSc in Cellular and Molecular Biology with a specialization in Human Genetics.

Shiraz University of Medical Sciences logoSS

Shiraz University of Medical Sciences

MD, Medicine

2003 - 2013

MD with specialty in Clinical Genetics. Formal degree certificate pending fulfilment of mandatory public health service commitment.

UA

University of Chamran Ahwaz

BSc, Genetics

2003 - 2006

BSc in Genetics.

Tech stack

Software and tools used professionally

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