Skip to main content
mohammad amin malekraeisiMM
Looking for a job

mohammad amin malekraeisi

@mohammadaminmalekrae

Bioinformatics researcher studying pancreatic cell states with single-cell RNA-seq and computational modeling.

Iran
Message

In my research collaboration with the Division of Pediatric Surgery at UPMC Children’s Hospital of Pittsburgh, I study how FAK inhibition affects pancreatic cell-state plasticity and reprogramming. I work with longitudinal single-cell RNA-seq data, developing workflows for integration, annotation, and cell-state analysis.

For a second collaboration with the same division, I analyzed single-cell RNA-seq data to investigate pancreatic ductal adenocarcinoma-associated changes in β-cell states. My work included quality control, annotation, differential expression, and characterization of β-cell heterogeneity.

As a freelance bioinformatician, I support academic research projects with omics analysis and interpretation. I develop reproducible Python and R workflows and deliver analysis pipelines, statistical analyses, and publication-ready figures.

My M.D. thesis investigated an amniotic membrane dressing with posaconazole-containing nanoparticles for fungal keratitis in vitro. I designed and evaluated a nanoliposome ocular drug-delivery system using release and permeation testing, MTT, hemolysis, and antifungal assays.

Experience

Work history, roles, and key accomplishments

UPMC Children's Hospital of Pittsburgh logoUP
Current

Bioinformatics Researcher

UPMC Children's Hospital of Pittsburgh

Jan 2024 - Present (2 years 10 months)

Investigated the cellular and molecular effects of FAK inhibition on pancreatic cell-state plasticity and reprogramming using longitudinal single-cell RNA-seq data. Performed quality control, developed computational workflows for single-cell integration, annotation, differential expression, trajectory and cell-state modeling, pathway analysis, and cell-cell communication.

SE
Current

Freelance Bioinformatician

Self Employed

Jan 2022 - Present (4 years 10 months)

Provide end-to-end bioinformatics and computational biology support for academic research projects involving omics data analysis and interpretation. Develop reproducible Python and R workflows for data preprocessing, integration, statistical modeling, feature prioritization, predictive modeling, and biological interpretation.

Education

Degrees, certifications, and relevant coursework

Iran University of Medical Sciences logoIS

Iran University of Medical Sciences

M.D., Medicine

2018 - 2026

M.D. degree from Iran University of Medical Sciences, with thesis on amniotic membrane dressing with nanoparticles for fungal keratitis.

Max Delbrück Center for Molecular Medicine logoMM

Max Delbrück Center for Molecular Medicine

Certificate of Achievement, Computational Genomics

2025 - 2025

Completed Module 3 of the Computational Genomics Course 2025, focusing on multi-omics integration using deep learning for precision oncology.

Max Delbrück Center for Molecular Medicine logoMM

Max Delbrück Center for Molecular Medicine

Certificate of Achievement, Computational Genomics

2025 - 2025

Completed Module 2 of the Computational Genomics Course 2025, focusing on spatial omics and spatial transcriptomics.

Tech stack

Software and tools used professionally

Get matched with your dream remote job

Sign up now and join over 1,000,000+ remote workers who receive personalized job alerts, curated job matches, and more for free!

Sign up
Himalayas profile for an example user named Frankie Sullivan