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Carlos Roca

@carlosroca

Director of Translational Bioinformatics at CSL R&D, advancing AI-supported drug research and target discovery.

Switzerland
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At CSL R&D, I lead Bioinformatics across Europe and the USA, supporting drug projects from preclinical research through early clinical development. My work includes target discovery and validation, biomarker discovery, and evaluating generative AI tools and biomedical foundation models for drug research.

Earlier, at the Babraham Institute and VIB - KU Leuven, I developed approaches for single-cell and multi-omics analysis, including AutoSpill for high-parameter flow cytometry, published in Nature Communications. Across my research career, I’ve developed computational methods spanning biomedical knowledge graphs, statistical modeling, and machine learning, with work published in journals including Cell and Cell Reports Methods.

Experience

Work history, roles, and key accomplishments

CSL Behring logoCB
Current

Director Translational Bioinformatics

CSL Behring

Dec 2025 - Present (9 months)

Building and leading the Bioinformatics team in Europe and USA, managing global stakeholder relationships, and leading bioinformatics support for drug projects in preclinical and early clinical development.

Babraham Institute, University of Cambridge logoBC

Senior Scientist, Bioinformatics Lead

Babraham Institute, University of Cambridge

Jan 2019 - Sep 2020 (1 year 8 months)

Pioneered analysis of multi-omics single-cell data, created a statistical test for dimensionality reduction methods, and devised a novel approach using Markov models and Bayesian statistics for immune cell traffic analysis.

Center for Brain & Disease Research, VIB - KU Leuven logoCL

Senior Bioinformatics Scientist

Center for Brain & Disease Research, VIB - KU Leuven

Nov 2017 - Mar 2019 (1 year 4 months)

Produced analysis pipelines for high-parameter flow cytometry and single-cell RNA-Seq data. Developed the AutoSpill algorithm for compensation in flow cytometry, adopted by BD/FlowJo and published in Nature Communications.

Aarhus University logoAU

Senior Research Associate

Aarhus University

Aug 2015 - Oct 2017 (2 years 2 months)

Contributed transcriptomics data analysis to six research papers on nanoparticle toxicity and created a novel normalization algorithm for transcriptomics data.

Education

Degrees, certifications, and relevant coursework

Massachusetts Institute of Technology logoMT

Massachusetts Institute of Technology

Cell Biology: Signaling, Cell Biology

2021 - 2021

Completed online course in Cell Biology: Signaling.

Massachusetts Institute of Technology logoMT

Massachusetts Institute of Technology

Cell Biology: The Cytoskeleton and Cell Cycle, Cell Biology

2021 - 2021

Completed online course in Cell Biology: The Cytoskeleton and Cell Cycle.

Massachusetts Institute of Technology logoMT

Massachusetts Institute of Technology

Cell Biology: Cell-Cell Interactions, Cell Biology

2021 - 2021

Completed online course in Cell Biology: Cell-Cell Interactions.

Massachusetts Institute of Technology logoMT

Massachusetts Institute of Technology

Cell Biology: Transport, Cell Biology

2020 - 2020

Completed online course in Cell Biology: Transport.

Harvard Medical School logoHS

Harvard Medical School

Foundational Concepts in Immunology, Immunology

2018 - 2018

Completed online course in Foundational Concepts in Immunology.

Rice University logoRU

Rice University

Fundamentals of Immunology, Part 3, Immunology

2017 - 2017

Completed online course in Fundamentals of Immunology, Part 3.

Massachusetts Institute of Technology logoMT

Massachusetts Institute of Technology

Molecular Biology, Part 3 - RNA Processing and Translation, Molecular Biology

2017 - 2017

Completed online course in Molecular Biology, Part 3 - RNA Processing and Translation.

Massachusetts Institute of Technology logoMT

Massachusetts Institute of Technology

Molecular Biology, Part 2 - Transcription and Transposition, Molecular Biology

2016 - 2016

Completed online course in Molecular Biology, Part 2 - Transcription and Transposition.

Massachusetts Institute of Technology logoMT

Massachusetts Institute of Technology

Molecular Biology, Part 1 - DNA Replication and Repair, Molecular Biology

2016 - 2016

Completed online course in Molecular Biology, Part 1 - DNA Replication and Repair.

Harvard University logoHU

Harvard University

Cell Biology: Mitochondria, Cell Biology

2016 - 2016

Completed online course in Cell Biology: Mitochondria.

University of Pennsylvania logoUP

University of Pennsylvania

Vital Signs, Human Biology

2015 - 2015

Completed online course in Vital Signs.

University of California, San Francisco logoUF

University of California, San Francisco

Genomic and Precision Medicine, Genomic Medicine

2014 - 2014

Completed online course in Genomic and Precision Medicine.

University of Illinois at Urbana-Champaign logoUU

University of Illinois at Urbana-Champaign

Emergence of Life, Biology

2014 - 2014

Completed online course in Emergence of Life.

Rice University logoRU

Rice University

Fundamentals of Immunology, Part 2, Immunology

2014 - 2014

Completed online course in Fundamentals of Immunology, Part 2.

Rice University logoRU

Rice University

Fundamentals of Immunology, Part 1, Immunology

2014 - 2014

Completed online course in Fundamentals of Immunology, Part 1.

University of Melbourne logoUM

University of Melbourne

Epigenetic Control of Gene Expression, Biology

2013 - 2013

Completed online course in Epigenetic Control of Gene Expression.

University of British Columbia logoUC

University of British Columbia

Useful Genetics, Genetics

2013 - 2013

Completed online course in Useful Genetics.

Massachusetts Institute of Technology logoMT

Massachusetts Institute of Technology

Introduction to Biology, Biology

2013 - 2013

Completed online course in Introduction to Biology.

Duke University logoDU

Duke University

Introductory Human Physiology, Human Physiology

2013 - 2013

Completed online course in Introductory Human Physiology.

University of Maryland logoUM

University of Maryland

Genes and the Human Condition, Genetics

2013 - 2013

Completed online course in Genes and the Human Condition.

University of Pennsylvania logoUP

University of Pennsylvania

Experimental Genome Science, Genome Science

2013 - 2013

Completed online course in Experimental Genome Science.

Duke University logoDU

Duke University

Introduction to Genetics and Evolution, Genetics and Evolution

2012 - 2012

Completed online course in Introduction to Genetics and Evolution.

ETH Zurich logoEZ

ETH Zurich

Postdoctoral Training, Quantitative and Computational Modeling

2009 - 2011

Postdoctoral training in quantitative and computational modeling at ETH Zurich, focusing on computational social science.

Universidad Carlos III de Madrid logoUM

Universidad Carlos III de Madrid

Ph.D., Applied Mathematics

2006 - 2009

Grade: Summa cum laude

Ph.D. in Applied Mathematics with a focus on Physics of Complex Systems, awarded Summa cum laude by unanimous decision.

Universidad Politécnica de Madrid logoUM

Universidad Politécnica de Madrid

M.Sc., Telecommunication Engineering

Grade: Sobresaliente

M.Sc. in Telecommunication Engineering with top grade (Sobresaliente).

Massachusetts Institute of Technology logoMT

Massachusetts Institute of Technology

Biochemistry: Biomolecules, Methods and Mechanisms, Biochemistry

2022 - 2022

Completed online course in Biochemistry: Biomolecules, Methods and Mechanisms.

Harvard University logoHU

Harvard University

Principles of Biochemistry, Biochemistry

2016 - 2016

Completed online course in Principles of Biochemistry.

Davidson College logoDC

Davidson College

Medicinal Chemistry, Chemistry

2014 - 2014

Completed online course in Medicinal Chemistry.

University of Kentucky logoUK

University of Kentucky

Advanced Chemistry, Chemistry

2014 - 2014

Completed online course in Advanced Chemistry.

University of Minnesota logoUM

University of Minnesota

Statistical Molecular Thermodynamics, Chemistry

2013 - 2013

Completed online course in Statistical Molecular Thermodynamics.

University of Illinois at Urbana-Champaign logoUU

University of Illinois at Urbana-Champaign

Introductory Organic Chemistry, Part 1, Chemistry

2013 - 2013

Completed online course in Introductory Organic Chemistry, Part 1.

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