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Carlos Roca
@carlosroca
Director, Head of Bioinformatics at CSL | Driving AI-powered drug discovery and development
SwitzerlandWhat I'm looking for
At CSL R&D, I lead Bioinformatics across Europe and the USA, supporting drug projects from preclinical research through early clinical development. My work includes target discovery and validation, biomarker discovery, and evaluating generative AI tools and biomedical foundation models for drug research and development.
Earlier, at the Babraham Institute (Cambridge, UK) and VIB - KU Leuven, I developed approaches for single-cell and multi-omics analysis, including AutoSpill for high-parameter flow cytometry, a current standard in industry and academia. Across my research career, I’ve developed computational methods spanning biomedical knowledge graphs, statistical modeling, and machine learning, with work published in journals including Cell and Nature Communications.
Experience
Work history, roles, and key accomplishments
Current
Director Translational Bioinformatics
CSL Behring
Dec 2025 - Present (11 months)
Building and leading the Bioinformatics team in Europe and USA, managing global stakeholder relationships, and leading bioinformatics support for drug projects in preclinical and early clinical development.
Associate Director Bioinformatics
CSL Behring
Nov 2022 - Nov 2025 (3 years)
Built and led the Bioinformatics team in Europe, managed global stakeholder relationships, and led bioinformatics support for drug projects in preclinical and early clinical development.
Contributed to drug projects in several therapeutic areas regarding target discovery, biomarker selection, and patient stratification. Designed and implemented machine learning and AI algorithms on biomedical knowledge graphs.
Senior Scientist, Bioinformatics Lead
Babraham Institute, University of Cambridge
Jan 2019 - Sep 2020 (1 year 8 months)
Pioneered analysis of multi-omics single-cell data, created a statistical test for dimensionality reduction methods, and devised a novel approach using Markov models and Bayesian statistics for immune cell traffic analysis.
Senior Bioinformatics Scientist
Center for Brain & Disease Research, VIB - KU Leuven
Nov 2017 - Mar 2019 (1 year 4 months)
Produced analysis pipelines for high-parameter flow cytometry and single-cell RNA-Seq data. Developed the AutoSpill algorithm for compensation in flow cytometry, adopted by BD/FlowJo and published in Nature Communications.
Senior Research Associate
Aarhus University
Aug 2015 - Oct 2017 (2 years 2 months)
Contributed transcriptomics data analysis to six research papers on nanoparticle toxicity and created a novel normalization algorithm for transcriptomics data.
Director of Research
Universitat Rovira i Virgili
Dec 2011 - Jul 2015 (3 years 7 months)
Responsible for a new research line on systems biology, establishing international collaborations and developing a graph-based approach for pathway analysis of omics data.
Postdoctoral Researcher
ETH Zurich
Aug 2009 - Oct 2011 (2 years 2 months)
Developed models of human behavior and analyzed data from behavioral experiments, with results published in PNAS and other journals.
NB
Senior Software Engineer
National Center for Biotechnology
Jul 2004 - Feb 2006 (1 year 7 months)
Validated image-processing algorithms for cryo-electron microscopy data used in protein structure identification.
EA
Senior Software Consultant
EADS-CASA
Nov 2001 - Jun 2004 (2 years 7 months)
Led an outsourced team, expanding it from two to six members, and advised on software development best practices. Developed communication, visualization, and algorithmic software for avionics systems.
Education
Degrees, certifications, and relevant coursework
Harvard Medical School
Foundational Concepts in Immunology, Immunology
2018 - 2018
Completed online course in Foundational Concepts in Immunology.
Rice University
Fundamentals of Immunology, Part 3, Immunology
2017 - 2017
Completed online course in Fundamentals of Immunology, Part 3.
Massachusetts Institute of Technology
Molecular Biology, Part 1 - DNA Replication and Repair, Molecular Biology
2016 - 2016
Completed online course in Molecular Biology, Part 1 - DNA Replication and Repair.
Harvard University
Principles of Biochemistry, Biochemistry
2016 - 2016
Completed online course in Principles of Biochemistry.
Massachusetts Institute of Technology
Molecular Biology, Part 2 - Transcription and Transposition, Molecular Biology
2016 - 2016
Completed online course in Molecular Biology, Part 2 - Transcription and Transposition.
Harvard University
Cell Biology: Mitochondria, Cell Biology
2016 - 2016
Completed online course in Cell Biology: Mitochondria.
University of Pennsylvania
Vital Signs, Human Biology
2015 - 2015
Completed online course in Vital Signs.
University of California, San Francisco
Genomic and Precision Medicine, Genomic Medicine
2014 - 2014
Completed online course in Genomic and Precision Medicine.
Davidson College
Medicinal Chemistry, Chemistry
2014 - 2014
Completed online course in Medicinal Chemistry.
Rice University
Fundamentals of Immunology, Part 1, Immunology
2014 - 2014
Completed online course in Fundamentals of Immunology, Part 1.
University of Illinois at Urbana-Champaign
Emergence of Life, Biology
2014 - 2014
Completed online course in Emergence of Life.
Rice University
Fundamentals of Immunology, Part 2, Immunology
2014 - 2014
Completed online course in Fundamentals of Immunology, Part 2.
University of Kentucky
Advanced Chemistry, Chemistry
2014 - 2014
Completed online course in Advanced Chemistry.
Duke University
Introductory Human Physiology, Human Physiology
2013 - 2013
Completed online course in Introductory Human Physiology.
University of Illinois at Urbana-Champaign
Introductory Organic Chemistry, Part 1, Chemistry
2013 - 2013
Completed online course in Introductory Organic Chemistry, Part 1.
University of British Columbia
Useful Genetics, Genetics
2013 - 2013
Completed online course in Useful Genetics.
Massachusetts Institute of Technology
Introduction to Biology, Biology
2013 - 2013
Completed online course in Introduction to Biology.
University of Minnesota
Statistical Molecular Thermodynamics, Chemistry
2013 - 2013
Completed online course in Statistical Molecular Thermodynamics.
University of Melbourne
Epigenetic Control of Gene Expression, Biology
2013 - 2013
Completed online course in Epigenetic Control of Gene Expression.
University of Pennsylvania
Experimental Genome Science, Genome Science
2013 - 2013
Completed online course in Experimental Genome Science.
University of Maryland
Genes and the Human Condition, Genetics
2013 - 2013
Completed online course in Genes and the Human Condition.
Duke University
Introduction to Genetics and Evolution, Genetics and Evolution
2012 - 2012
Completed online course in Introduction to Genetics and Evolution.
ETH Zurich
Postdoctoral Training, Quantitative and Computational Modeling
2009 - 2011
Grade: no grades awarded
Activities and societies: Postdoctoral training and research
Universidad Carlos III de Madrid, Spain
Ph.D. in Applied Mathematics
2006 - 2009
Universidad Politécnica de Madrid
M.Sc., Telecommunication Engineering
Grade: Sobresaliente (top grade)
Activities and societies: M.Sc. in Telecommunication Engineering
Availability
Looking for a job
Location
SwitzerlandAuthorized to work in
United Kingdom
Spain
Germany
France
ItalySalary expectations
60k-120k CHF
Social media
Job categories
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