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Ayche Maksoud

@aychemaksoud

Nanoscience MSc candidate at Osnabrück University building reproducible proteomics pipelines for planarian regeneration research.

Germany

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What I'm looking for

I'm motivated to apply my multidisciplinary skills to molecular medicine, cellular-mechanism research, and data-driven biological discovery.

At Osnabrück University, I designed and implemented a reproducible R-based pipeline for quantitative proteomics of cellular and extracellular vesicles across planarian regeneration stages. I used it to clean and quality-check data, assess replicate consistency, and identify regeneration-associated protein expression patterns.

I also support Oxford Nanopore direct-RNA transcriptomics analysis in R, including sequencing quality control and differential-expression analysis. I produce reproducible RMarkdown reports and visualizations to support interpretation and scientific reporting.

My practical research has included studying extracellular-vesicle uptake during planarian regeneration, as well as membrane fusion and inflammatory cell-death mechanisms. I’ve applied laboratory methods including microinjection, immunofluorescence, protein purification, Western blotting, and fluorescence microscopy.

Experience

Work history, roles, and key accomplishments

Current

Master's Thesis Researcher – Proteomics & Bioinformatics

Current

Osnabrück University

Jan 2026 - Present (9 months)

Designed and implemented a reproducible R-based analysis pipeline for quantitative proteomics of cellular and extracellular-vesicle samples across planarian regeneration stages. Applied multivariate and statistical methods to assess replicate consistency and identify regeneration-associated protein expression patterns.

R Bioconductor tidyverse Proteomics Transcriptomics Data Quality Control PCA Hierarchical clustering Pearson Correlation Fisher Information Differential Expression R Markdown Oxford Nanopore

Planarian Extracellular-Vesicle Research Practical

Osnabrück University

Jan 2024 - Dec 2025 (1 year 11 months)

Investigated extracellular-vesicle uptake during planarian regeneration using planarian handling, microinjection, fluorescent EV labelling, anti-PIWI immunofluorescence and fluorescence microscopy.

Planarian Handling Microinjections Fluorescent EV Labelling Immunofluorescence Fluorescence Microscopy

Signalling in Immunity and Cell Death Practical

Osnabrück University

Jan 2024 - Dec 2024 (11 months)

Studied GasderminD-mediated membrane permeabilisation and inflammatory cell-death mechanisms using fluorescent giant unilamellar vesicle (GUV) membrane models and fluorescence microscopy.

Fluorescence Microscopy GUV Membrane Models Cell Death Mechanisms

Molecular Cell Biology and Biochemistry Practical

Osnabrück University

Jan 2024 - Dec 2024 (11 months)

Investigated Rab-GTPase regulation, intracellular protein trafficking and membrane fusion. Applied yeast transformation, bacterial protein expression, affinity purification, SDS-PAGE, Western blotting, pull-down assays and fluorescence microscopy.

Genetic Transformation Bacterial Protein Expression Affinity Purification SDS PAGE Western Blot Pull Down Assays Fluorescence Microscopy

Education

Degrees, certifications, and relevant coursework

Osnabrück University

Master of Science, Nanosciences

2023 -

Pursuing a Master of Science in Nanosciences with a major in Biology and minor in Chemistry, including a master's thesis in Animal Physiology focused on reproducible R-based analysis of proteomics data.

HarvardX via edX

Data Science: Visualization, Data Science

2026 - 2026

Completed the Data Science: Visualization course, focusing on data visualization methods and tools.

HarvardX via edX

Data Science: Wrangling, Data Science

2026 - 2026

Completed the Data Science: Wrangling course, covering data wrangling techniques and best practices.

Lebanese University – Faculty of Science

Bachelor of Science, Life and Earth Sciences

2019 - 2022

Grade: Satisfactory

Completed a Bachelor of Science in Life and Earth Sciences, covering molecular biology, genetics, genomics, microbiology, immunology, biochemistry, physiology, ecology, and biostatistics, with practical laboratory training.