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AS@ashibarsapir
Oncology scientist and medical director with 15+ years of experience.
IsraelI am an oncology scientist and medical director with over 15 years of experience in biologic drug discovery and AI-powered clinical solutions. My journey has been marked by a passion for leveraging technology to transform precision oncology and improve patient outcomes. I have successfully led antibody and ADC programs, and directed AI-driven platforms that enhance clinical trial access for cancer patients.
Throughout my career, I have designed and implemented AI-powered clinical trial-matching tools, collaborated with major pharmaceutical companies, and built partnerships that drive innovation in cancer care delivery. My PhD work focused on immune profiling and personalized medicine, which has equipped me with a robust understanding of tumor immunology and therapeutic antibody discovery.
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Work history, roles, and key accomplishments
Biolojic Design
Jan 2024 - Present (1 year 10 months)
Leads research and development for novel ADC programs targeting solid tumors. Designs and executes functional cell-based assays to evaluate antibody efficacy, optimizing antibody candidates via yeast display and high-throughput screening.
Leal Health
Jan 2021 - Present (4 years 10 months)
Directed the Lung and Mesothelioma Cancer Medical Team, developing AI-powered clinical decision tools to match patients with clinical trials. Validated medical components of the digital platform, ensuring high accuracy, regulatory compliance, and clinical precision.
Merck KGaA
Jan 2016 - Present (9 years 10 months)
Completed PhD thesis work within Merck KGaA’s R&D division, investigating tumor immunology using yeast display antibody libraries derived from tumor-infiltrating B cells. Developed novel screening strategies for therapeutic antibody discovery and led various screening techniques including yeast display and FACS sorting.
Merck KGaA
Jan 2014 - Present (11 years 10 months)
Led antibody-drug conjugate development, overseeing the process from initial target screening through to validation. Managed project timelines and resources to ensure successful program progression.
Merck KGaA
Jan 2009 - Present (16 years 10 months)
Participated in end-to-end therapeutic antibody development processes, contributing to various stages of research and development. Supported experimental design and execution within oncology and immuno-oncology R&D initiatives.
Serono S.A.
Jan 2000 - Present (25 years 10 months)
Monitored and controlled Interferon beta (Rebif®) production in bioreactors, ensuring adherence to manufacturing protocols and quality standards. Managed upstream processing operations to optimize yield and purity.
Degrees, certifications, and relevant coursework
TDPhD, Biochemistry
Completed PhD thesis work focusing on the evaluation of yeast display Fab libraries derived from tumor-infiltrating B cells. This research supported tumor immunology and personalized medicine initiatives.
HJM.Sc.Agr, Biochemistry & Food Sciences
Grade: Cum Laude
Conducted research for Master's thesis on the immunochemical and molecular detection of Atenolol in food and environmental samples. Graduated with Cum Laude honors.
HJB.Sc, Animal Science & Agricultural Economics
Studied foundational principles in Animal Science and Agricultural Economics. Gained knowledge in areas relevant to agricultural practices and economic aspects of the field.
Software and tools used professionally
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