Director, Program Management

About Peptilogics: Leaders in Scalable, Rational Design

Peptilogics is a clinical-stage biotechnology company that designs and develops novel peptide therapeutics. The company leverages machine learning, automation, and peptide synthesis to build platforms for science at scale. With its foundations in drug development and engineering, the company’s platforms vertically integrate proprietary hardware, software, bioinformatics, chemistry, and molecular biology to advance basic research, target validation, and clinical trials.

Job Title: Director, Program Management

Location(s): Pittsburgh, PA or Remote

Job Status: Full-Time

Position Overview

The Director, Program Management is responsible for leading high-priority, cross-functional development programs across Peptilogics’ portfolio. This individual will serve as the central point of coordination for planning, execution, risk management, and cross-functional communication, ensuring alignment with strategic goals, timelines, and budgets. The role requires a hands-on, execution-driven leader who brings structure to ambiguity and drives accountability across program teams.

While this role does not initially include direct reports, the Director will mentor and support the professional development of a Manager-level team member in Corporate Operations. This is a non-supervisory relationship, focused on guidance, collaboration, and cross-functional enablement.

Essential Functions

• Develop and maintain integrated development plans and timelines with clear visibility into critical path activities
• Coordinate cross-functional program execution across clinical, nonclinical, regulatory, manufacturing, and operations
• Build and maintain program budgets and forecasts in partnership with Finance, including scenario planning
• Identify and manage risks through proactive tracking, mitigation planning, and cross-functional alignment
• Lead regular cross-functional meetings, project reviews, and governance presentations
• Develop dashboards and reporting tools to provide program visibility to senior leadership and executive stakeholders
• Support design review processes and ensure timely and actionable team feedback
• Track and manage internal and external resources, vendors, and contract milestones in alignment with program objectives
• Reinforce a culture of accountability, operational excellence, and cross-functional

Additional Duties and Responsibilities

• Provide structure and visibility into program-level operational needs to support internal coordination across corporate functions
• Collaborate with Corporate Operations to align on resource planning, vendor coordination, and external deliverables tied to program execution
• Partner with internal teams to ensure quality documentation and SOP timelines are integrated into program plans
• Mentor and guide the Manager, Corporate Operations through regular engagement, helping them navigate program dependencies and stakeholder alignment
• Provide input into corporate reporting, board materials, and cross-functional KPIs where tied to program progress
• Contribute to the development of internal tools and workflows that enhance project execution, transparency, and communication
• Promote and uphold safe work practices and compliance with company procedures
• Support other strategic and functional initiatives as assigned

Required Qualifications and Skills

• Bachelor’s degree in a life science, engineering, or related technical field; advanced degree (MBA, MS) preferred
• 10+ years of program/project management experience in the biotech or pharmaceutical industry
• Demonstrated experience managing clinical-stage development programs
• PMP or equivalent project management certification preferred
• Prior experience supporting cross-functional budget planning or board-level reporting preferred
• Experience in portfolio management, executive reporting, or investor-facing deliverables preferred
• Deep knowledge of the end-to-end drug development process including CMC, nonclinical, clinical, and regulatory
• Demonstrated success leading complex cross-functional development programs
• Ability to operate with limited oversight, manage ambiguity, and make data-driven decisions
• Strong communication skills with ability to engage and influence stakeholders at all levels
• Proven ability to structure and manage large-scale program plans, including risk and scenario management
• Experience in a startup or growth-stage biotech company preferred

Our Commitment to Equal Opportunity

Peptilogics is proud to be an equal opportunity employer. We make hiring decisions based on qualifications, experience, and potential—without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other protected status. We welcome candidates from all backgrounds to apply.