BenchSciBE

Engineering Manager - Knowledge Engineering

We’re resolving the complexity of disease biology to help advance your science.

BenchSci

Employee count: 51-200

United Kingdom only
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We are looking for an experienced Knowledge Engineering Manager to join our Knowledge Representation team. You will be reporting to the Director of Engineering, Data ML. Using your specialism in knowledge engineering you will spearhead our team towards groundbreaking advancements in knowledge engineering, representation and management. The ideal candidate will be deeply versed in the intricacies of knowledge graphs, graph databases, Knowledge representation techniques, and ideally experienced in the application of graph data science for insightful knowledge extraction and enrichment.
The most successful candidates for this role will be experienced knowledge engineers who have remained hands-on, are most comfortable providing technical leadership and delivering complex knowledge engineering solutions such as knowledge graphs. This role is perfect for a leader who is technically adept and passionate about guiding a team toward innovative solutions in how we represent knowledge. The successful candidate will not only be a people and technical leader, but also a mentor, coach, and a role model in our organisation.

You Will:

  • Be a people leader of a small (approx 4-6) team of knowledge engineers and data engineers.
  • Be hands-on as needed in coding, data modelling, as well as participating in system design, code pairing, PR reviews, building data pipelines, and writing TDDs (technical design documents).
  • Own and drive execution of the technical roadmap for your team in line with the technical and product roadmaps.
  • Provide engineering/technical leadership on Knowledge Engineering projects that contribute to the data in BenchSci’s Knowledge Graph.
  • Be responsible for building and maintaining BenchSci’s knowledge graph, including our biological ontologies that form part of it.
  • Lead the harmonisation and integration of diverse biological ontologies into a cohesive knowledge base, utilising standards like RDF (Resource Description Framework), OWL (Web Ontology Language), and technologies like Neo4j.
  • Advocate for and implement leading graph database technologies, as well as RDF Stores and Triple-stores where relevant, to construct scalable, performant and robust systems.
  • Work closely with senior and lead engineers within your team, and on other teams, to ensure alignment on technical solutions and delivery.
  • Liaise closely with stakeholders from other functions including product, science and project management.
  • Help ensure the adoption of engineering best practices and state-of-the-art knowledge engineering approaches at BenchSci.Uphold best practices in data modelling, representation, and management.
  • Drive agile practices within the team, and lead certain agile rituals.
  • Take a leadership role in our recruiting, hiring, and onboarding processes.
  • Provide mentorship and carry out regular 1:1 meetings with direct reports.Work with your team to continuously drive improvements in ways of working, productivity and quality of work product

You Have:

  • 5+ years hands-on experience working in knowledge engineering, some of which is in the biological or science domains.
  • 3+ years in technical leadership roles.
  • 2+ years of experience working as a knowledge engineering manager.
  • A Master’s or PhD in Computer Science, Bioinformatics, or a closely related field, with a strong emphasis on knowledge engineering, possibly also including machine learning.
  • A proven track record technically leading the delivery of complex knowledge engineering projects with high-performing teams leveraging state-of-the-art technologies and techniques.
  • Have remained technically hands-on and have maintained a high cadence of code contributions over the last 12 months.
  • Extensive background in knowledge engineering with a proven track record building and deploying large scalable performant knowledge graphs using graph databases and associated technologies (e.g., Neo4j, Amazon Neptune, TigerGraph, JanusGraph, ArangoDB, and OrientDB).
  • Deep understanding of when and how to deploy different knowledge graph-related technologies such as labeled property graphs, semantic networks, RDF, and RDFS.
  • Proficient in various knowledge representation techniques such as ontologies, taxonomies, and frames.
  • Experience developing or extending ontologies to model domain knowledge in a structured form with an understanding of ontology languages such as OWL (Web Ontology Language).
  • Domain expertise working in knowledge acquisition of biological data and experience working with biological ontologies (e.g. Mondo, ChEBI, KEGG, UniProt, Reactome etc).
  • Familiar with mid-level biological ontologies, such as BioLink, and how they can be leveraged to integrate (disambiguation, canonicalisation, standardisation) disparate biological ontologies.
  • Extensive skills in data modelling in graphs and relational databases, as well as graph and relational database design and management.
  • Exceptional programming skills, predominantly in Python, with exposure to other languages, along with graph querying languages such as Cypher and SPARQL.
  • Outstanding leadership qualities, coupled with a passion for mentoring and advancing a team of talented engineers.
  • Well-versed in Agile software development methodologies and practices.
  • Outstanding verbal and written communication skills. Can clearly explain complex technical concepts/systems to engineering peers and non-engineering stakeholders alike.
  • A growth mindset that ensures you’re up-to-date with state-of-the-art and cutting-edge advances related to knowledge engineering, and are actively engaging with the relevant tech communities.

Nice to have:

  • Knowledge of how to leverage ML, Natural Language Processing (NLP) and LLMs for knowledge discovery and acquisition to build knowledge graphs from unstructured data.
  • Familiar with state-of-the-art approaches and techniques for generating graph embeddings, and vectorization of knowledge graphs.
  • Knowledge of how to leverage ML techniques, and LLMs (including RAG) for understanding and extracting data in knowledge graphs.
  • Have worked alongside machine learning engineers carrying out in-graph machine learning on knowledge graphs you have constructed.
  • Familiarity with how to maximize knowledge discovery and to enrich knowledge graphs (KG) by reasoning over and inferencing from existing KG data using graph data science (GDS), graph machine learning (GML), and Graph Neural Networks (GNNs) approaches.

Benefits and Perks:

An engaging remote-first culture
A great compensation package that includes BenchSci equity options
A robust vacation policy plus an additional vacation day every year
Company closures for 14 more days throughout the year
Flex time for sick days, personal days, and religious holidays
Comprehensive health and dental benefits.
Annual learning development budget
A one-time home office set-up budget to use upon joining BenchSci
An annual lifestyle spending account allowance
Generous parental leave benefits with a top-up plan or paid time off options
The ability to save for your retirement coupled with a company match!

About BenchSci:

BenchSci's mission is to exponentially increase the speed and quality of life-saving research and development. We empower scientists to run more successful experiments with the world's most advanced, biomedical artificial intelligence software platform.
Backed by Generation Investment Management, TCV, Inovia, F-Prime, Golden Ventures, and Google's AI fund, Gradient Ventures, we provide an indispensable tool for scientists that accelerates research at 16 top 20 pharmaceutical companies and over 4,300 leading academic centers. We're a certified Great Place to Work®, and top-ranked company on Glassdoor.

Our Culture:

BenchSci relentlessly builds on its strong foundation of culture. We put team members first, knowing that they're the organization's beating heart. We invest as much in our people as our products. Our culture fosters transparency, collaboration, and continuous learning.
We value each other's differences and always look for opportunities to embed equity into the fabric of our work. We foster diversity, autonomy, and personal growth, and provide resources to support motivated self-leaders in continuous improvement.
You will work with high-impact, highly skilled, and intelligent experts motivated to drive impact and fulfill a meaningful mission. We empower you to unleash your full potential, do your best work, and thrive. Here you will be challenged to stretch yourself to achieve the seemingly impossible. Learn more about our culture.
Diversity, Equity and Inclusion: We're committed to creating an inclusive environment where people from all backgrounds can thrive. We believe that improving diversity, equity and inclusion is our collective responsibility, and this belief guides our DEI journey. Learn more about our DEI initiatives.
Accessibility Accommodations: Should you require any accommodation, we will work with you to meet your needs. Please reach out to [email protected].

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About the job

Apply before

May 28, 2024

Posted on

Mar 29, 2024

Job type

Full Time

Experience level

Manager

Location requirements

Hiring timezones

United Kingdom +/- 0 hours

About BenchSci

Learn more about BenchSci and their company culture.

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We’re resolving the complexity of disease biology to help advance your science.

Using AI and proprietary visual machine learning, we’ve built the world’s first evidence-backed map of disease biology. Because we believe that when scientists understand what has already been done, they can understand the feasibility of what is yet to be discovered.

We taught a computer to read and understand experiments like a biologist

Our founders Tom Leung, David Q. Chen, Elvis Wianda, and Liran Belenzon met at the U of T Creative Destruction Lab in 2015. Together they built, tested, and validated an AI solution to the antibody reproducibility crisis. This captured the attention of Google’s AI fund Gradient Ventures, who led BenchSci’s A-round and raised $10M to develop the technology and the business.

Then built an enterprise AI solution to antibody selection

In 2017, BenchSci launched its first application, AI-Assisted Antibody Selection, to help scientists reduce experimental failure. The solution used both experiment-specific text ML and proprietary vision ML models that could understand the type of experiment being conducted. Next, our team then built relationships between those data points with proprietary bioinformatics ontologies. Best of all, we made these results searchable in an intuitive user interface.

Now we power research at the world’s biggest institutions

Within three years, more than 4,300 leading academic research institutions and 16 of the top 20 pharma companies were using our AI solutions. More than 50,000 scientists began relying on BenchSci to support their experiment decisions.

Project Butterfly—The world’s first evidence-backed map of disease biology

What scientists discovered was that BenchSci and our visual ML had built the first objective map of the underlying biology of disease. So, working in secret with top partners and global pharma R&D leaders, we launched Project Butterfly—an attempt to use this transformative technology to solve the biggest challenges in pre-clinical research. iNovia and TCV supported this initiative with a $50M Series C round.

Our next step: ASCEND

The portfolio success platform developed during Project Butterfly was given the name ASCEND, as it is designed to take the discovery and development of medicine to new heights. It augments scientists by giving them an unmatched understanding of disease biology in a platform that democratizes that understanding in all therapeutic areas. With ASCEND, our aim is to increase the speed and yield of the R&D portfolio by multiples, not percentages.

Series D Funding

BenchSci announces the completion of its Series D funding round led by Generation Investment Management. The significant investment enables BenchSci to further enhance the AI-powered platform ASCEND, expand offerings, and continue to empower scientists with the tools they need to accelerate drug discovery and improve patient outcomes.

Employee benefits

Learn about the employee benefits and perks provided at BenchSci.

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Home Office Budget

BenchSci supports remote work with a $1000 CAD budget for employees to set up their home office.

Learning & Development

BenchSci invests in its employees' growth with a $2000 CAD annual budget for learning and development.

Unlimited Flex Time

Employees at BenchSci enjoy unlimited flex time, sick days, personal days, and time off for religious holidays.

Parental Leave Top-Up

BenchSci offers generous parental leave benefits with a top-up plan and paid time options to support new parents.

View BenchSci's employee benefits
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