Senior Manager, Pharmacometrics and Data Sciences

Cencora is seeking a Senior Manager, Pharmacometrics and Data Sciences to apply his/her knowledge in pharmacometrics and modelling and simulation (M&S) to quantitative pharmacology and sciences in non-clinical and clinical pharmacokinetic (PK) / pharmacodynamic (PD).

This role is a remote role and can based either in the United States of America or in Europe.

As Senior Manager, Pharmacometrics & Data Sciences you will contribute to the development and execution of pharmacometrics Model-informed Drug Development (MIDD) approaches that support drug development and regulatory submissions. The ideal candidate will have a strong background in pharmacometrics and quantitative pharmacology modeling, with demonstrated project management skills. This role will involve cross-functional collaboration with internal and external stakeholders to ensure the successful application of quantitative modeling and simulation techniques to optimize drug development programs.

Responsibilities:

• Development, execution and interpretation of pharmacometric analyses, including population PK and PK/PD models, Non-Compartmental Analysis (NCA), exposure-response modeling, clinical trial simulations.

Technical Expertise

• Develop and validate pharmacometric models to support dose selection, trial design, and decision-making.

• Analyze and interpret complex pharmacokinetic (PK) and pharmacodynamic (PD) data, integrating results with clinical and preclinical data.

• Author and review technical protocols, analysis plan, reports and scientific publications. Review regulatory documents in area of expertise.

• Propose innovative quantitative pharmacology approaches and optimize modeling processes.

Cross-Functional Collaboration

• Collaborate with clinical pharmacology, biostatistics, regulatory, and clinical development teams to align pharmacometric strategies with program objectives.

• Communicate modeling results and their implications to cross-functional teams and senior management

• Represent the company in meetings with academic institutions and industry forums as a pharmacometric subject matter expert.

Project Management

• Oversee multiple pharmacometric projects, ensuring timely delivery of high-quality outputs.

• Ensure contact with the client

• Manage project oversight, quality and budget control.

• Ensure compliance with regulatory guidelines and internal quality standards

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Education:

• Pharm D or Ph.D. in Pharmaceutical Sciences or Biomedical Engineering, with specialization in pharmacometrics
• A Master’s degree with substantial relevant experience will also be considered.

Work Experience:

• 3-5 years of experience in pharmacometrics within the pharmaceutical or biotechnology industry.
• Demonstrated expertise in population PK/PD modeling, exposure-response analysis, and clinical trial simulations.

Skills and Knowledge:

• Proficiency in pharmacometric software (essentially NONMEM and R, PKanalyx or Phoenix Winonlin). Knowledge of PKSim, Monolix, MATLAB is a plus.
• Strong analytical and problem-solving skills, with the ability to synthesize complex data into actionable insights.
• Good written and verbal communication skills, with the ability to present complex concepts to diverse audiences.
• Organizational and project management skills, with the ability to manage multiple priorities.
• Knowledge of the pharmaceutical industry, including preclinical and early clinical development and the underlying pharmacometrics issues
• Minimum knowledge of basic of IT
• Autonomous, concentrated and high-quality work
• Ability to work in team and manage more junior people in the context of an international team working remotely
• Sense of responsibility
• Knowledge of English

What Cencora offers

​Benefit offerings outside the US may vary by country and will be aligned to local market practice. The eligibility and effective date may differ for some benefits and for team members covered under collective bargaining agreements.

Affiliated Companies

Equal Employment Opportunity

Cencora is committed to providing equal employment opportunity without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, age, disability, veteran status or membership in any other class protected by federal, state or local law.

The company’s continued success depends on the full and effective utilization of qualified individuals. Therefore, harassment is prohibited and all matters related to recruiting, training, compensation, benefits, promotions and transfers comply with equal opportunity principles and are non-discriminatory.

Cencora is committed to providing reasonable accommodations to individuals with disabilities during the employment process which are consistent with legal requirements. If you wish to request an accommodation while seeking employment, please call 888.692.2272 or email hrsc@cencora.com. We will make accommodation determinations on a request-by-request basis. Messages and emails regarding anything other than accommodations requests will not be returned