Open to opportunities

Layla Ghaffari

@laylaghaffari

Message

I design intelligence systems with governance frameworks for reliable AI and biotech.

United States

Message

What I'm looking for

I’m looking to design governance-first intelligence and experimental systems—turning underdefined environments into reliable, scalable, and reproducible operation through first-principles reasoning, evaluation frameworks, and rigorous validation.

I’m an Intelligence Systems Designer and Systems Architect focused on identifying governing structures in complex, underdefined environments, then designing frameworks that make system behavior reliable, scalable, and reproducible. Across artificial intelligence, biotechnology, and education, I turn ambiguous or non-operational domains into structured, functioning systems using first-principles reasoning and experimental design.

In my current role, I directed conceptual architecture and technical strategy for AI cognition systems—defining foundational frameworks for reasoning, memory, authority, orchestration, and human–AI interaction. I also developed governed AI decision-making and system-level specifications that integrate AI, cognitive science, and systems architecture into structured intelligence frameworks.

Earlier, I worked as an Associate Scientist diagnosing failure modes in biological systems and redesigning them for scalability. I engineered an end-to-end recombinant protein production platform, optimizing serum-free expression and improving downstream purification workflows, while establishing internal experimental infrastructure to support scalable biologics production.

I also built compliance and documentation systems for regulated laboratory operations, standardizing technical documentation into audit-ready workflows within six months. I bring that same rigor to experimental design, protocol creation, and validation/quality control practices—so teams can reliably execute, measure outcomes, and reproduce results.

Experience

Work history, roles, and key accomplishments

Current

Chief Intelligence Officer & Partner

Current

ArcheForge

Nov 2025 - Present (8 months)

Directed the conceptual architecture and technical strategy for AI cognition systems, defining foundational frameworks for reasoning, memory, authority, and orchestration. Led cross-disciplinary development of governed AI decision-making and early-stage patent-pending technologies.

Systems Architecture Memory Orchestration Human AI Interaction AI Governance

Associate Scientist

Cello

Jun 2025 - Dec 2025 (6 months)

Diagnosed breakdowns in a primary amebocyte culture system and identified toxic media conditions and non-scalable assumptions limiting viability. Engineered scalable cultivation and reproducible differentiation methodologies via first-principles redesign of media, seeding, and growth dynamics.

Amebocyte Culture Diagnostics Toxic Media Identification Media Composition Redesign Suspension Based Shake Flask Systems Vessel Geometry Volumetric Constraints

Associate Scientist

American Gene Technologies

Oct 2022 - Jul 2023 (9 months)

Architected an end-to-end recombinant protein production platform spanning cell culture, expression, filtration, and purification workflows. Designed serum-free expression systems and downstream chromatography-based purification strategies, and established internal experimental infrastructure and documentation systems.

Recombinant Proteins Filtration Purification Serum Free Expression Systems Downstream Purification Strategy

Specialist I

VaLogic LLC

Oct 2019 - Aug 2020 (10 months)

Developed and implemented compliance and documentation systems for regulated laboratory operations, including validation protocols and quality control infrastructure. Standardized technical documentation into an audit-ready system and coordinated validation protocol execution across clients and stakeholders.

Compliance Documentation Quality Control Quality Control Service Workflows

Teaching Assistant & Lab Manager

Frederick Community College

Dec 2018 - May 2019 (5 months)

Designed and implemented laboratory systems and infrastructure for a tissue culture curriculum, including equipment configuration, inventory systems, and experimental workflows. Co-taught hands-on labs and developed structured learning materials for biotechnology training, emphasizing aseptic technique, media formulation, and cell culture methodology.

Tissue Culture Curriculum Design Lab Configurations Aseptic Technique Cell Culture