Senior Integration Engineer - Cold Chain & Pharmaceutical Logistics

PAXAFE is a logistics orchestration & decision intelligence SaaS platform that helps Cold Chain planning, logistics and quality teams consolidate their transportation data agnostically, digitize and automate product quality and lane qualification decisions, and operationalize prescriptive recommendations in the transportation network.

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Acting as the cold chain trust layer whose mission is to drive towards zero transportation waste, PAXAFE works with cold chain manufactures and service providers to reduce product loss, improve operational efficiencies and make more informed decisions in real-time.

PAXAFE's vision is to become the backend intelligence infrastructure that powers every temperature, time and value-sensitive shipment in the world.

PAXAFE is backed by great VCs (Framework Venture Partners, Ubiquity Ventures, Venture53, RoseCliff Ventures, etc.) and CVCs (Microsoft M12, Northwestern Mutual, Greenlight Re)

The Role

We're seeking an experienced Senior Integration Engineer to join our engineering team and lead the development of critical data integrations for our cold chain logistics platform. You'll be responsible for building and maintaining complex integrations that process shipment tracking data, device telemetry, and temperature monitoring feeds from diverse logistics partners and IoT devices—enabling real-time visibility and proactive risk management for temperature-sensitive pharmaceutical shipments.

This role requires someone who thrives on solving complex data challenges, from debugging international geocoding issues to optimizing high-volume telemetry processing workflows and reconciling conflicting data across multiple vendor systems. You'll work directly with major pharmaceutical clients to ensure their critical shipments maintain temperature integrity throughout the supply chain.

What You'll Do

Integration Development & Data Processing

• Build and maintain production integrations using Prismatic.io, handling complex payload transformations and multi-step workflows
• Process and normalize shipment tracking data from 3PL partners (UPS, Kuehne+Nagel, World Courier, DHL, FedEx)
• Implement robust error handling and retry logic for unreliable vendor APIs ensuring 100% of data is captured
• Design device selection algorithms to optimize telemetry data processing
• Create matching logic for automated shipment routing decisions

Real-time Monitoring & Alert Systems

• Build integration deviation detection and alerting workflows
• Process device telemetry streams from multiple IoT providers (Sensitech, Tag-n-Trac, Elpro, Tive, Samsara, Controlant, Roambee, etc.)
• Calculate packaging thermal life and predict temperature breaches
• Implement 3PL/carrier milestone processing for shipment status updates
• Design dashboards for real-time integration health visibility for internal and external stakeholders

Data Quality & Validation

• Debug and resolve geocoding issues with international addresses using Mapbox and other APIs
• Implement comprehensive data validation for vendor payloads
• Build data quality monitoring and anomaly detection systems
• Create reconciliation workflows for mismatched shipment and device data
• Handle API (REST, GraphQL, SOAP), EDI (AS2), and legacy (email, SFTP) transmission implementations

Database & Infrastructure

• Design and optimize Supabase database schemas for high-volume telemetry data
• Write complex PostgREST queries for data retrieval and aggregation
• Implement efficient upsert patterns for real-time data updates
• Build data archival and retention strategies
• Create database migration scripts and maintain schema documentation

Customer Implementation & Support

• Debug production issues across multiple client environments
• Optimize integration performance for high-volume data streams
• Support Linear project management workflows
• Document PAXAFE integration workflows, schemas, and other specifications

Who We're Looking For

Required Technical Skills

• 4+ years building production data integrations with complex transformation requirements
• Expert-level JavaScript/TypeScript for integration development
• Strong experience with iPaaS platforms (Prismatic.io strongly preferred)
• Proficiency with PostgreSQL and modern database patterns (Supabase/PostgREST experience a plus)
• Experience with geocoding APIs and address normalization challenges
• Understanding of webhook patterns, REST APIs, and real-time data streaming
• Frontend experience for building integration monitoring dashboards

Critical Domain Experience (one or more of the following)

• Cold chain logistics and temperature-controlled shipments (pharmaceutical strongly preferred)
• Experience with 3PL data formats and tracking systems
• IoT device integration and telemetry processing
• Understanding of GxP compliance and pharmaceutical logistics requirements
• Knowledge of thermal packaging and temperature excursion management
• EDI/AS2 protocol experience

Problem-Solving Expertise

• Proven ability to debug complex data quality issues across multiple systems
• Experience handling inconsistent vendor data formats and missing fields
• Skills in reverse-engineering undocumented APIs and payload structures
• Understanding of retry strategies and error recovery patterns
• Experience with high-volume data processing optimization

Key Competencies

• Obsessive attention to data quality and validation
• Ability to context-switch between multiple integration issues
• Strong debugging skills with distributed systems
• Experience managing vendor relationships and escalations
• Clear technical documentation and communication skills

What Success Looks Like

First 30 Days:

• Master our Prismatic integration patterns and existing workflows
• Successfully debug and resolve at least one production integration issue
• Understand our core vendor data formats

First 90 Days:

• Own end-to-end delivery of a new integration
• Create comprehensive documentation for your integration

First 6 Months:

• Lead the technical design for a major client implementation
• Reduce integration error rates by implementing better validation
• Mentor team members on complex debugging techniques
• Contribute to our integration platform architecture decisions

Technologies You'll Work With Daily

• Integration Platform:Prismatic.io
• Languages: JavaScript/TypeScript, SQL, Python
• Databases: Supabase (PostgreSQL), PostgREST, SmartSheet
• APIs: Mapbox, various 3PL/IoT APIs
• Monitoring: New Relic, Grafana
• Project Management: Linear
• Data Formats: JSON, XML, EDI, CSV transformations
• Protocols: Webhooks, AS2, REST, GraphQL, SOAP

Why This Role Matters

Every integration you build directly impacts the safe delivery of life-saving medications. When you successfully process a temperature alert or accurately track a shipment's location, you're helping ensure that critical pharmaceuticals arrive at the right temperature, at the right time. Your work prevents billions of dollars in product loss and, more importantly, ensures patients receive the medications they need.

Why You'll Love Working Here

·High-impact mission: Every project directly supports safe, compliant delivery of the world’s most important products worldwide (e.g. vaccines, life-saving therapies, food, etc.)

·PAXAFE has entered an exciting growth phase which provides for [and requires] a great deal of autonomy & leadership at every role & every level

·AI innovation playground: Work at the cutting edge of LLM and agentic AI applications in enterprise B2B software. Shape how pharmaceutical companies leverage AI to transform their supply chains. You'll be building AI products that solve real problems, not demos.

·Startup ownership: Join a cohesive, collaborative team where your ideas shape the future of our platform

·Remote-first flexibility: Work from anywhere (Central / Eastern US preferred)

·Cutting-edge tech stack: Work with the latest AI/ML technologies alongside modern infrastructure. Technologies include: LLMs & Agentic AI | Azure | Python | Prismatic | Supabase | PostgreSQL | LavinMQ | Inngest | IoT | shadcn | Linear | Figma.

·Growth opportunity: Step into a foundational technical leadership role with direct visibility to PAXAFE's executive team and Fortune 500 pharmaceutical customers. Shape the product direction at a high-growth startup.

·Comprehensive benefits: Competitive base salary, equity participation, five weeks PTO, and full healthcare coverage

Our Core Values

·Create Magic: Deliver products that exceed customer expectations and solve real problems elegantly

·Own With Pride: Take ownership of outcomes and deliver with excellence

·Navigate With Intent: Make strategic decisions with clarity and purpose

·Think Deep, Act Fast: Balance thorough analysis with rapid execution

·Enjoy the Journey: Celebrate wins and maintain perspective

·X-hibit Teamwork: Collaborate across functions and support each other's success

·Tackle With Empathy: Understand customer and team needs deeply before proposing solutions

Ready to tackle complex integration challenges in cold chain logistics?

Please include:

1. Your resume highlighting integration and data pipeline experience
2. A brief description of the most complex data quality issue you've debugged
3. Any experience with pharmaceutical, cold chain, or logistics domains
4. Your approach to handling unreliable vendor APIs and data inconsistencies

Note: Experience with our specific tech stack is preferred but not required. We value problem-solving ability and domain expertise over specific tool experience.