GeneDxGE

Engineering Manager, Data Platform & Applications

GeneDx is a pioneering leader in clinical genomics, specializing in genetic testing to accelerate diagnoses and improve patient outcomes, especially in pediatric care.

GeneDx

Employee count: 1001-5000

Salary: 191k-191k USD

United States only

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest rare disease data sets. For more information, please visit www.genedx.com.

Summary

GeneDx, the world's leading genomic diagnostics company, is seeking a thoughtful, technically strong, and people-focused Engineering Manager to lead our Back Office Services team within the Data Platform organization. This team is the backbone of our internal data ecosystem, responsible for ingesting, modeling, and delivering operational data that powers decision-making across the business, from laboratory logistics to billing operations.

Job Responsibilities

  • Lead and mentor a team of engineers building React and Python-based web applications that surface data and insights to stakeholders across the business.
  • Oversee the development and integration of dynamic visualizations and dashboards, including embedded Sigma graphs.
  • Collaborate with Data Engineering and Product teams to define and deliver data-driven applications that support workflows in clinical operations, lab logistics, and commercial analytics.
  • Define and drive the technical vision and roadmap for internal data apps, with a focus on usability, performance, and maintainability.
  • Promote best practices in frontend and backend development, code quality, observability, and secure design.
  • Support the professional growth of your team through mentorship, feedback, and career development.
  • Partner with recruiting and leadership to attract and retain top talent, while fostering a collaborative and inclusive culture.

Education, Experience, and Skills

  • Proven experience (typically 2+ years) managing engineering teams building web applications in a production environment.
  • 5+ years of hands-on engineering experience with modern frontend and backend technologies (e.g., React, TypeScript, Python, Flask/FastAPI).
  • Experience integrating embedded analytics tools such as Sigma, Looker, or Tableau.
  • Strong product and user empathy—able to translate stakeholder needs into elegant, intuitive applications.
  • Experience working in cross-functional teams and collaborating with product managers, designers, and data engineers.
  • Skilled at navigating ambiguity, scoping MVPs, and aligning team execution with broader platform goals.
  • Excellent communication skills and a collaborative, low-ego approach to leadership.
  • Experience in a regulated environment (e.g., healthcare, biotech, or finance) is a plus.

People Manager

  • Yes

Certificates, Licenses, Registrations

  • None

Physical Demands

  • Ability to stand, walk, and sit for extended periods.

Work Environment

  • Work is primarily performed in a remote office setting

#LIREMOTE

Pay Transparency, Budgeted Range$153,053—$191,317 USD

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Science - Minded, Patient - Focused.

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most.

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.

SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.

From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:

TECHNICAL EXPERTISE

  • High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
  • Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.

CLINICAL EXPERTISE

  • Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
  • Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
  • Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.

Learn more About Us here.

Our Culture

At GeneDx, we are dedicated to cultivating an environment where creativity and innovation thrive. We believe in the power of community and collaboration, where diverse perspectives are embraced, and every voice contributes to our shared success. Our team is a vibrant mix of professionals who challenge and support each other in equal measure, fostering growth both personally and professionally. When you join us, you're not just taking on a job—you're joining a movement. A movement that champions curiosity, embraces change, and believes in making an impact, one patient at a time. Cultural principles we live by:  

  • Be bold in our vision & brave in our execution. 
  • Communicate directly, with empathy. 
  • Do what we say we're going to do.  
  • Be adaptable to change.  
  • Operate with a bias for action.  

Benefits include:

  • Paid Time Off (PTO)
  • Health, Dental, Vision and Life insurance
  • 401k Retirement Savings Plan
  • Employee Discounts
  • Voluntary benefits

GeneDx is an Equal Opportunity Employer.

All privacy policy information can be found here.

About the job

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Posted on

Job type

Full Time

Experience level

Manager

Salary

Salary: 191k-191k USD

Location requirements

Hiring timezones

United States +/- 0 hours

About GeneDx

Learn more about GeneDx and their company culture.

View company profile

Innovation through genetic testing is revolutionizing healthcare at GeneDx. As a leader in clinical genomics and rare disease diagnostics, we specialize in exome and genome sequencing with a primary focus on pediatric care. Our mission is to empower patients and healthcare providers by providing fast and accurate genetic diagnoses, ensuring that every individual receives the targeted medical attention they deserve. With a commitment to reducing the diagnostic odyssey, we harness one of the world's largest genomic databases to deliver clinically actionable insights backed by unparalleled expertise.

At GeneDx, we understand the complexities associated with genetic disorders and the urgent need for timely identification. By offering advanced genomic technologies, we aim to improve health outcomes and families' lives through earlier interventions. Our industry-leading tests are part of the standard of care, demonstrating a higher diagnostic yield than traditional methods. Through collaborations with healthcare professionals and ongoing research, we continue to evolve our testing methodologies, striving for a future where genetic testing is accessible, accurate, and integral to patient care everywhere.

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GeneDx

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GeneDx hiring Engineering Manager, Data Platform & Applications • Remote (Work from Home) | Himalayas