Looking for a job

Олександер Забєгалов

@oleksander

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I build retinal organoid models and stem-cell research platforms.

Switzerland

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What I'm looking for

I’m looking to expand advanced 3D cell-culture systems for therapeutic and fundamental research, particularly retinal disease, organoid vascularisation, and tissue engineering, in academic, industrial, or start-up environments.

At the University of Lausanne, I engineered a double-reporter mouse embryonic stem cell line to trace retinal progenitors and photoreceptors, screened 200+ clones, and produced hundreds of mouse and human retinal organoids.

I use CRISPR/Cas9, pluripotent stem-cell culture, differentiation, and organoid analysis to advance translational ophthalmology. I’m looking to expand advanced 3D culture systems for retinal disease research, vascularisation, and tissue engineering in academic, industrial, or start-up settings.

Experience

Work history, roles, and key accomplishments

Professional development

Career Break

May 2025 - Apr 2026 (11 months)

Work on market proposition, career coaching, evaluation of career paths, skills development (French language, Python programming), exploration of personal values and motivation, research on leading Swiss and international stem cell biology labs, companies, and start-ups; refining of the job profile, networking with leading Swiss life science experts.

PHD Researcher

University of Lausanne - UNIL

Oct 2017 - May 2025 (7 years 7 months)

- Engineered a novel double-reporter mouse embryonic stem cell line enabling simultaneous tracing of retinal progenitors and photoreceptors, creating a platform applicable to translational ophthalmology and cell-based therapy research.
- Successfully executed complex CRISPR/Cas9 double-nickase genome editing to insert a large construct into pluripotent stem cells with error-free integration confir

Master Thesis Student

Charité - Universitätsmedizin Berlin

Dec 2015 - Sep 2016 (9 months)

- Generated three induced pluripotent stem cell (iPSC) lines carrying NDUFS4 mutation causing Leigh syndrome, enabling disease modeling of mitochondrial dysfunction.
- Co-authored publication in a high-impact journal following contribution to revision experiments.
- Streamlined workflow for microglia motility time-lapse analysis, improving analytical efficiency and reproducibility.

Guest Researcher

DESY

May 2011 - Apr 2012 (11 months)

- Finalized analysis of D*-meson properties in deep inelastic scattering experiments.
- Developed algorithms to calculate physics variables and generate analytical graphs from collision datasets.