Open to opportunities

Jaya Madala

@jayamadala

Message

I build regulated enterprise AI and data platforms that accelerate pharmaceutical development.

United States

Message

What I'm looking for

I'm looking to lead enterprise AI, data science, and precision medicine platforms where I can turn regulated healthcare data into production solutions that improve development speed, patient outcomes, and business value.

I'm currently driving digital and AI strategy for AstraZeneca Global Technical Operations, delivering GxP-validated production AI systems integrated with LIMS, GQCLIMS, and MES. My work reduced analysis cycle times by 30–40% across 30+ statistical analyses and 50+ regulatory protocols.

Previously, I architected AWS-based precision medicine and personalized healthcare platforms at Amgen and Genentech, integrating clinical metadata, omics, imaging, EHR, claims, and genomics data for translational and clinical teams. These enterprise platforms supported reproducible research, MLOps, governance, and more than 1,000 researchers.

Across Roche Diagnostics, Saama Technologies, Genomic Health, and KLA-Tencor, I've led data science teams, real-world data studies, biomarker analytics, predictive modeling, and regulated software quality efforts. I build practical AI solutions—from LLM extraction pipelines to human-in-the-loop risk tools—while aligning responsible AI, privacy, compliance, and business value.

Experience

Work history, roles, and key accomplishments

Current

AI Director, Data Science & Digital - Global Technical Operations

Current

AstraZeneca

Dec 2024 - Present (1 year 9 months)

Defined digital/AI strategy for Global Technical Operations, delivered GxP-validated production AI suite, and designed LLM-based extraction pipelines. Led hands-on AI engineering and people leadership across manufacturing, quality, and regulatory teams.

AI Strategy MLOps CI CD AWS Azure Generative AI LLM GxP LIMS GQCLIMS MES Responsible AI HIPAA GDPR ICH Python Claude Code Gemini 3 Pro AZAI Gateway

Senior Principal Product Owner - Precision Medicine

Amgen

May 2024 - Dec 2024 (7 months)

Architected and built Precision Medicine Clinical Data platform on AWS implementing FAIR principles for integration of clinical metadata, omics, and imaging data. Implemented tiered access, data contracts, and quality controls.

AWS Clinical Data Imaging Data Governance

Senior Principal Data Scientist & Product Specialist – PHC

Genentech

Jan 2020 - May 2024 (4 years 4 months)

Led ingestion and classification of diverse data sources into AWS cloud infrastructure and managed data science team developing insights using advanced analytics. Championed adoption of Data Science best practices and served as Product Owner for GxP compliance AWS PTC Bioinformatics Cloud platform.

AWS MLOps Data Science Machine Learning Deep Learning Statistical Modeling GxP Product Ownership Team Management

Senior Principal Data Scientist - DSS, DIS

Roche Diagnostics

Jun 2016 - Dec 2019 (3 years 6 months)

Built cross-functional partnerships and delivered RWD analyses for oncology biomarkers and infectious disease. Applied statistical inference, machine learning, and AI methods across diverse projects and led a high-performance data science team.

Machine Learning AI EMR Claims R Tableau CRO Management Team Leadership

Data Science Manager

Saama Technologies

May 2015 - May 2016 (1 year)

Owned data science roadmap for Hi-Tech, Insurance, and Healthcare verticals and led development of predictive models including risk scores and subrogation models.

predictive modeling Logistic Regression Random Forest Gradient Boosting Product Strategy Stakeholder Management

Biostatistician

Genomic Health Inc.

Feb 2008 - Apr 2015 (7 years 2 months)

Performed methylation analysis for liquid biopsy characterization using NGS technology and conducted statistical analysis for gene assay studies. Executed stability studies and designed study protocols with statistical methodologies.

Biostatistics NGS Methylation Statistical Analysis Study Design

Senior Software QA Engineer

Genomic Health Inc.

Aug 2004 - Jan 2008 (3 years 5 months)

Designed and executed test procedures for LIMS software ensuring HIPAA/CLIA compliance. Automated unit testing using NUnit and functional, regression, and acceptance testing using SilkTest.

LIMS HIPAA NUnit Silk Test Testing Automation QA