United States onlyAs a community, the University of Rochester is defined by a deep commitment to Meliora - Ever Better. Embedded in that ideal are the values we share: equity, leadership, integrity, openness, respect, and accountability. Together, we will set the highest standards for how we treat each other to ensure our community is welcoming to all and is a place where all can thrive.
Job Location (Full Address):
Remote Work - Pennsylvania, Harrisburg, Pennsylvania, United States of America, 17120Opening:
Worker Subtype:
RegularTime Type:
Full timeScheduled Weekly Hours:
40Department:
900100 Empire Discovery InstituteWork Shift:
UR - Day (United States of America)Range:
UR URG 120Compensation Range:
$178,474.00 - $285,558.00The referenced pay range represents the minimum and maximum compensation for this job. Individual annual salaries/hourly rates will be set within the job's compensation range, and will be determined by considering factors including, but not limited to, market data, education, experience, qualifications, expertise of the individual, and internal equity considerations.
Responsibilities:
Implements the Empire Discovery Institute’s (EDI) strategic research and development roadmap and provides exemplary scientific input into EDI’s research and development programs to support the overall strategy set by institutional leaders. Leads the research, translational, and preclinical development of new drug candidates from target selection, hit-to-lead identification/optimization, drug candidate selection, Investigational New Drug (IND) enabling studies, to early clinical development. Leads medicinal chemistry efforts in the pharmaceutical and biotechnology industry and maintains a thorough understanding of the drug discovery and development process. Articulates EDI’s strategy to research collaborators, investors, and pharmaceutical industry partners.Essential Functions:
- Provides scientific leadership in identifying and developing novel preclinical drug development opportunities in close collaboration with academic partners and investigators.Leads and manages EDI’s drug discovery efforts through a variety of approaches, including medicinal chemistry, high-throughput screening (HTS), computer-aided drug design (CADD), and fragment-based drug discovery approaches.
- Establishes the department’s strategic roadmap for drug candidate selection, advancement, out-licensing, and commercialization in collaboration with EDI’s CEO and scientific advisory panel.
- Provides scientific input, guidance, and oversight of external vendors working to establish, optimize, and apply molecular and cell-based assays, in vitro and in vivo pharmacology models, and biomarker approaches to advance EDI programs.
- Delivers formal presentations at medical, scientific, strategic partnering, and fundraising meetings on behalf of EDI.
- Oversees budget planning and negotiating, in collaboration with EDI’s CEO, in addition to monitoring spending and general fiscal responsibilities.
- Other duties as assigned.
Minimum Education & Experience:
- PhD degree or higher in science and/or related medical field and 10 years of experience within the pharmaceutical and/or biotech industry, including experience in multiple therapeutic areas with small molecule and biologics required.
- Or equivalent combination of education and experience.
- Proven experience in successfully progressing drug candidates from discovery to IND and early clinical development required.
Knowledge, Skills & Abilities:
- Demonstrated management and leadership skills, with expertise in drug discovery and development process, with strategic thinking abilities, and strong verbal and written communication skills required.
- Strong problem-solving skills and sound judgment to accelerate strategic and project decision-making, and evidence for successful cross-disciplinary stakeholder negotiation to drive portfolio and project results required.
- Demonstrated ability to translate research into pathway and target identification and validation required.
- Ability to work effectively with diverse groups of people, the capacity to listen, and the ability to gain trust and inspire others to further the Institute’s mission and priorities required.
- Ability to prioritize, delegate, and oversee a complex organizational environment that includes collaborating with multiple academic research institutions, corporate partners, venture capital firms, research foundations, external vendors/CROs, and governmental agencies required.
- Capable of independently assuming project and licensing evaluation leadership roles to define and achieve EDI’s objectives and portfolio priorities required.
- Ability to be fiscally responsible and to lead decision-making in resource planning, finance, project management, and outsourced CRO relationships required.
The University of Rochester is committed to fostering, cultivating, and preserving an inclusive and welcoming culture to advance the University’s Mission to Learn, Discover, Heal, Create – and Make the World Ever Better. In support of our values and those of our society, the University is committed to not discriminating on the basis of age, color, disability, ethnicity, gender identity or expression, genetic information, marital status, military/veteran status, national origin, race, religion, creed, sex, sexual orientation, citizenship status, or any other characteristic protected by federal, state, or local law (Protected Characteristics). This commitment extends to non-discrimination in the administration of our policies, admissions, employment, access, and recruitment of candidates, for all persons consistent with our values and based on applicable law.
