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Wilberforce Osei

@wilberforceosei

Clinical pharmacologist and oncology pharmacist specializing in PK/PD, pharmacogenomics, and early-phase oncology drug development.

United States

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What I'm looking for

I seek roles that combine clinical oncology pharmacology and quantitative modeling to influence precision-medicine strategies, early-phase development, and translational research in collaborative, multidisciplinary teams.

I am a clinical pharmacologist and oncology pharmacist with combined clinical and industry experience across precision medicine, PK/PD modeling, and pharmacogenomics. I hold a PhD in Clinical Pharmaceutical Sciences and a PharmD, and I have led the implementation of precision medicine approaches including pharmacogenetics and population PK modeling.

In clinical roles I provide direct patient care, medication management, guideline development, and multidisciplinary collaboration to optimize oncology therapy; in industry and regulatory roles I have supported early-phase oncology trials, safety and PK interpretation, protocol drafting, and regulatory document preparation. My research includes PBPK/PopPK modeling, development and validation of pharmacogenomics pipelines from NGS/WES data, and translational biomarker evaluation.

I combine hands-on clinical practice with quantitative modeling skills (NONMEM, Simcyp, Monolix) and bioinformatics (Python, R, IGV, Aldy) to bridge bedside care and drug development. I am motivated to apply precision-medicine and modeling expertise to improve therapeutic outcomes and inform trial and regulatory strategy.

Experience

Work history, roles, and key accomplishments

Current

Clinical Specialty Pharmacist

Current

St. Vincent Hospital

Jan 2024 - Present (2 years 2 months)

Provide direct oncology patient care including medication initiation, monitoring, reconciliation, and counselling; developed oncology guidelines and managed formulary to improve therapy safety and access.

Oncology Medication Therapy Management Formulary Management Clinical Guidelines Patient Counseling

Postdoctoral Fellow

AbbVie

Oct 2024 - Jan 2025 (3 months)

Supported early-phase oncology trials by interpreting safety and PK data, drafting protocol and regulatory documents, and informing trial strategy for first-in-human studies.

Clinical safety Clinical Operations Cross Functional Collaboration

Clinical Pharmacologist

IU Simon Comprehensive Cancer Center

Mar 2021 - Oct 2024 (3 years 7 months)

Led implementation of precision medicine approaches including pharmacogenomics and PK/PD modeling to optimize oncology therapies and contributed to clinical protocol development.

Pharmacogenomics PD Modeling Precision Medicine Protocol Development NONMEM Regulatory Writing

ORISE Research Fellow

U.S. Food and Drug Administration

Jun 2024 - Aug 2024 (2 months)

Conducted translational and modeling projects in the Office of Clinical Pharmacology, including PBPK applications for therapeutic proteins and biomarker strategy evaluations.

Research Design

ORISE Research Fellow

U.S. Food and Drug Administration

Jun 2023 - Aug 2023 (2 months)

Evaluated translational biomarker strategies and regulatory considerations to support fit-for-purpose biomarker development in clinical pharmacology.

Biomarker Strategies Regulatory Clinical Pharmacology Evaluation

Clinical Pharmacology Intern

AbbVie

Jun 2022 - Aug 2022 (2 months)

Reviewed dose optimization strategies for pediatric populations in immune-mediated conditions to support clinical development decisions.

Clinical Development literature review

Clinical Pharmacology Intern

Vertex Pharmaceuticals

Jun 2021 - Aug 2021 (2 months)

Developed population PK models for VX-864 and its metabolite using NONMEM to inform dosing and exposure assessments.

Population PK NONMEM Data Analysis Pharmacometrics

Adjunct Lecturer

Bowie State University

Jan 2014 - Jan 2020 (6 years)

Designed and taught undergraduate pharmacology courses, led curriculum development, and implemented active learning methods to increase student engagement.

Teaching Curriculum Development Pharmacology

Lead Pharmacist

Georgetown University Hospital

Jan 2014 - Jan 2020 (6 years)

Managed inpatient pharmacy services, mentored staff, reduced medication errors, and supported P&T committee decisions and clinical protocol implementation.

Protocols Workflow Optimization Quality Improvement

Education

Degrees, certifications, and relevant coursework

Indiana University

Master of Science, Clinical Research

2022 - 2024

Activities and societies: Research fellowships with FDA Office of Clinical Pharmacology; clinical pharmacology internships and modeling projects.

Master of Science in Clinical Research focused on translational biomarker strategies and clinical pharmacology.

Purdue University

Doctor of Philosophy, Clinical Pharmaceutical Sciences

2020 - 2024

Activities and societies: Dissertation research on pharmacogenotype extraction; PopPK and PBPK modeling projects; publications in clinical pharmacology and oncology.

PhD in Clinical Pharmaceutical Sciences with a dissertation on computational pharmacogenotype extraction using NGS and somatic WES in precision oncology.