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Jashan Preet Singh

@jashanpreetsingh2

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I engineer biomaterial platforms to study cardiac ageing and mechanobiology.

Singapore

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What I'm looking for

I'm seeking a postdoctoral role in ageing and mechano-matrix biology, where I can develop engineered tissue and biomaterial platforms to study physical regulation of cell and tissue behaviour across the human healthspan.

At the Mechanobiology Institute, NUS, I engineered stiffness-gradient hydrogels and patterned nano-biointerfaces to show how matrix mechanics program cardiac cell mechano-sensing independently of age.

I build experimental platforms spanning engineered tissue models, biomaterials, imaging, spatial genomics, mechanical characterization, and drug testing. I also commissioned a new lab, validated equipment, authored SOPs, trained researchers, and developed analysis pipelines in Python, R, and MATLAB.

My work also includes patient-specific 3D-printed liver and prostate phantoms for clinical training, graphene-based SPR biosensors for malaria detection, and paper-based aptasensors. I'm seeking postdoctoral work in ageing and mechano-matrix biology across the human healthspan.

Experience

Work history, roles, and key accomplishments

Doctoral Research

Mechanobiology Institute, NUS

Jan 2021 - Jul 2026 (5 years 6 months)

Engineered stiffness-gradient hydrogels and nano-patterned bio-interfaces to study how matrix mechanics govern cardiac cell mechano-sensing independent of age. Integrated multimodal datasets including fluorescence imaging, spatial genomics, and mechanical characterization.

Mechanobiology Hydrogel Fabrication Spatial Genomics Python R Matlab Laboratory Commissioning

Research Scientist

3D Printing & Prototyping Laboratory, Duke-NUS

Aug 2025 - Dec 2025 (4 months)

Designed and fabricated patient-specific liver phantoms for clinical palpation training, iterating against surgeon feedback. Conceptualized plug-and-play phantom systems and prepared development timelines for clinical deployment.

3D Printing CAD Phantom Fabrication

MSc Research

University of Dundee

Mar 2019 - Mar 2020 (1 year)

Reconstructed prostate and peripheral anatomy from MRI/CT scans via image segmentation and fabricated synthetic tissue-mimicking phantoms for robotic surgery training. Validated phantoms against human prostate on weight, geometry, and stiffness via MRI and structured urologist testing.

Segmentation Materialize Mimics 3D Printing MRI Tensile Testing

Undergraduate Projects

Indian Institute of Technology, Roorkee

Mar 2015 - Mar 2018 (3 years)

Built carbon-nanotube aptasensors on paper-based microfluidic devices and gold-nanoparticle colorimetric sensors for small-molecule detection in adulterated milk samples. Cloned and expressed Candida virulence proteins as vaccine candidates and developed biofilm growth and inhibition assays.

Microfluidics Molecular Cloning Protein Expression Ni NTA Affinity Chromatography Biofilm Assays

Visiting Scientist

University of Manchester

May 2017 - Jul 2017 (2 months)

Developed a graphene-based surface plasmon resonance biosensor for ultrasensitive malaria detection using variable-angle spectroscopic ellipsometry. Designed DNA-aptamer binding chemistry protocols and quantified binding by fluorescence microscopy.

DNA Aptamers Graphene

Education

Degrees, certifications, and relevant coursework

Mechanobiology Institute, National University of Singapore

Doctor of Philosophy, Mechanobiology

2021 - 2026

Activities and societies: Head, Graduate Committee; Winner, 3-Minute Thesis Competition

Doctoral research on engineered stiffness-gradient hydrogels and nano-patterned bio-interfaces to study how matrix mechanics govern cardiac cell mechano-sensing independent of age.

University of Dundee

Master of Science, Medical Imaging

2019 - 2020

Grade: Gold Medallist

Activities and societies: Teaching Assistant

MSc research focused on fabricating synthetic tissue-mimicking prostate models for robotic surgery training, including image segmentation and 3D printing.