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Intern, Clinical Operations Execution Optimization

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit elusive frontier targets within notorious growth and survival pathways, with particular emphasis on the RAS and mTOR signaling pathways.

Revolution Medicines

Employee count: 501-1000

Salary: 67k-81k USD

United States only

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Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS‑addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC‑6236), a RAS(ON) multi‑selective inhibitor; elironrasib (RMC‑6291), a RAS(ON) G12C‑selective inhibitor; zoldonrasib (RMC‑9805), a RAS(ON) G12D‑selective inhibitor; and RMC‑5127, a RAS(ON) G12V‑selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity

The Clinical Operations Summer Intern will support a strategic initiative focused on optimizing study‑level execution and operational alignment to the Clinical Operations Handbook (V2.0). The intern will conduct a structured review of active clinical studies to assess consistency, tool utilization, and workflow execution from protocol finalization through site activation.

Key Responsibilities

  • Select 1–2 active clinical studies for detailed assessment.
  • Evaluate use of RAID logs, Study Dashboards, Vendor Oversight Plans, and Startup Timelines.
  • Document end‑to‑end workflows from protocol finalization to site activation.
  • Identify gaps, redundancies, and inconsistencies in process execution.
  • Conduct structured interviews with COLs and CTAs.
  • Shadow CSET meetings to observe dashboard and RAID utilization.
  • Review Smartsheet tools and Egnyte folder structures.
  • Compare real‑world execution against Clinical Operations Handbook processes.

Deliverables

  • Current‑state workflow maps with annotated pain points.
  • Tool consistency matrix across selected studies.
  • Prioritized, actionable process improvement recommendations.
  • Updated mock dashboard or tracker templates (if applicable).

Impact

  • Reduce variability in study‑level execution.
  • Clarify ownership and functional handoffs.
  • Improve dashboard clarity for leadership review.
  • Strengthen inspection readiness through documented alignment.

Required Skills, Experience and Education

  • Pursuing a Bachelor’s or Master’s degree in Life Sciences, Public Health, Clinical Research, Business, or related field.
  • Excellent communication skills.
  • Interest in clinical trial operations and process optimization.

Preferred Skills

  • Strong analytical and organizational skills.
  • Proficiency in Microsoft Office; familiarity with Smartsheet a plus.

Base Pay Salary Range

$67,000 - $81,000 USD

EEO Statement

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

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About the job

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Job type

Intern

Experience level

Salary

Salary: 67k-81k USD

Location requirements

Hiring timezones

United States +/- 0 hours

About Revolution Medicines

Learn more about Revolution Medicines and their company culture.

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The journey of Revolution Medicines began in 2014, born from a collective passion to confront some of the most formidable challenges in cancer treatment. Headquartered in the heart of the biotech hub of Redwood City, California, the company was founded by a visionary team including Kevan Shokat, Michael Fischbach, and Martin Burke, with Mark A. Goldsmith taking the helm as CEO. Their ambitious mission from the outset was to discover and develop novel therapies for patients with RAS-addicted cancers, a group of malignancies that account for a staggering 30% of all human cancer diagnoses and have historically been notoriously difficult to treat. The founders recognized that conventional approaches had failed to effectively target the active, 'on' state of the RAS proteins that drive tumor growth, leaving a significant unmet need for countless patients.

This recognition sparked a revolutionary approach. The company pioneered its proprietary TRIPOD platform, a novel drug discovery engine designed to create therapies that can bind to and inhibit the active form of RAS. This platform became the cornerstone of their research and development efforts, enabling the creation of a deep pipeline of RAS(ON) inhibitors. The initial years were marked by intensive scientific exploration and strategic fundraising, including a pivotal Series A financing of $45 million in 2015 led by Third Rock Ventures. This early investment fueled the advancement of their discovery platform and set the stage for a series of clinical breakthroughs. As the company evolved, it continued to attract significant investment and forge strategic partnerships, steadily advancing its lead candidates through rigorous preclinical and clinical trials. Today, Revolution Medicines stands as a late-stage clinical oncology company, relentlessly pursuing its goal to transform the treatment landscape for RAS-addicted cancers and offer new hope to patients and their families.

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Revolution Medicines

Company size

501-1000 employees

Founded in

2014

Chief executive officer

Mark A. Goldsmith

Employees live in

View company profile

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