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ProfluentPR

Machine Learning Research Intern

Profluent is an AI-first protein design company focused on developing generative models to create novel proteins for transformative applications in biomedicine.

Profluent

Employee count: 51-200

United States only

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Profluent is an AI-first protein design company. Founded in 2022, we develop deep generative models to design and validate novel, functional proteins to revolutionize biomedicine. Based in Emeryville, CA, we are backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures, and have raised over $150M to date.

The Machine Learning (ML) team at Profluent is looking for a creative and motivated intern to drive research into new technologies for protein design. This position offers an opportunity to leverage advances at the forefront of machine learning for language processing, geometric representation, and proteins. Interns will have broad exposure to the technologies across the platform, including cross-functional interactions with the wet lab and teams regularly deploying new models and algorithms towards specific protein design goals.

Responsibilities

  • Contribute to ML research advancing the state-of-the-art in deep learning for protein sequence, structure, and function and its application to protein design
  • Work with a research mentor and the broader ML team to advance a summer research project for peer-reviewed publication or internal deployment
  • Analyze, interpret, and organize results and present progress to colleagues in regular research meetings

Qualifications

  • Current PhD Student (or equivalent industry experience) in Applied Math, Computer Science, Computational Biology, Machine Learning, Natural Language Processing, Statistics, or a related field
  • Experience with conceiving of, implementing, and developing novel machine learning methodology
  • Experience with modern deep learning frameworks such as Pytorch or Jax

Preferences (but not required)

  • Publications at major machine learning conferences (NeurIPS, ICML, ICLR) or scientific journals (Nature, Science, Nature Biotech, Nature Methods, PNAS)
  • Familiarity with foundational biology of proteins and nucleic acids
  • Experience developing machine learning models for proteins (language models, structure prediction, design)

What We Offer

  • Work on moonshot projects at the frontier of AI and biology
  • Mentorship from leading experts in bioinformatics, machine learning, and synthetic biology
  • A dynamic, mission-driven environment with the resources of a fast-growing, well-funded startup
  • Competitive internship compensation and benefits

Profluent Bio, Inc is an equal opportunity employer promoting diversity and inclusion in the workspace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law.

About the job

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Job type

Full Time

Experience level

Entry-level

Education

Postgraduate degree

Experience accepted in place of education

Location requirements

Hiring timezones

United States +/- 0 hours

About Profluent

Learn more about Profluent and their company culture.

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Grounded in nature, authored by AI. Proteins are the molecular machines enabling life’s biological functions. The next frontier is authoring new biology, and with AI, we have the power to write the future—creating solutions that transform medicine, agriculture, and beyond. At Profluent, we turn possibilities into reality, one protein at a time.

The world’s first AI-designed gene editor, OpenCRISPR, demonstrates authorship in action. Profluent’s AI writes proteins, whether inspired by natural scaffolds or designed from scratch. Our expert team combines machine learning and biology to unlock solutions to complex challenges in protein design. From new therapeutics to industrial enzymes, our AI-authored proteins are revolutionizing how we address challenges across diverse fields.

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Profluent

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