Senior Clinical Sciences Manager

JoinImmaticsandshape thefuture ofcancerimmunotherapy; one patient at atime!

Immaticsis committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting ofPRAME, a target expressed in more than 50 cancers. Ourcutting-edgescience and robust clinical pipeline form the broadestPRAMEfranchise with the mostPRAMEindications and modalities, spanning TCR T-cell therapies and TCRbispecifics.

Why Join Us?

• Innovative Environment:Help topioneeradvancementsin cancer immunotherapy.

• Collaborative Culture:Be part ofa diverse team dedicated to your professionalgrowth.

• Global Impact:Contribute to therapies thatmakealasting impactonpatientsglobally.

Role Overview

We are seeking a Senior Clinical SciencesManagerto support the execution of our clinical trials, including the SUPRAME (IMA203-301) study. The Senior Manager willbe responsible forsupporting patient journey navigation, primarily for U.S. sites, and updating patient-facing and clinical trial materials. In addition, this role will contribute to protocol development, conduct literature research, support trial outcome reporting, and deliver training to internal and external stakeholders.

Reportsto:Director, Clinical Sciences
Location:FullyRemote

Salary Range:$155,000 – 175,000

Basic Qualifications:

• Bachelor’s degree in biology, pharmacy, or a related scientific field

• 7+ years of experience conducting literature research using clinical and medical databases

• Demonstrated experience supporting clinical trial activities, including protocol and patient-facing materials

• Experience training site staff or internal teams on clinical trial protocols and materials

PreferredQualifications:

• Master’s degree in biology, pharmacy, or a related scientific field

• Experience supporting regulatory documentation (e.g., IRB submissions, RFIs)

• Experience working in oncology or cell therapy clinical development

• Advanced ability to translate complex scientific data into clear, actionable insights and presentations

• Experience working cross-functionally in a global clinical trial environment

In thisrole youwill:

• Serve as a key point of contact for clinical trial protocol and patient-facing material inquiries from sites and internal teams

• Support patient journey navigation, including proactive management of screening activities

• Contribute to authoring and updating clinical trial documents, including protocols, reports, and investigator materials

• Support preparation of responses for IRBs and regulatory authorities

• Deliver site training on clinical trial protocols and patient-facing materials (e.g., SIVs)

• Conduct literature research and develop presentations to support clinical activities

• MaintainaccurateeTMF documentation and filing

Travel required:up to20% travelrequired, domestically and internationally.

Qualified candidates willparticipatein a structured interview process, which includes:

• An initialrecruiter phone screen (conducted via video)

• A recruiter-facilitated introduction and interview with the hiring leader and key stakeholders (via video)

• A final-stage interview, which may include an in-person meeting at our U.S. Headquarters in Houston, TX

Work authorization/security clearancerequirements: 

Legal eligibility to work in the United States isrequired.Immaticsparticipates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment  

Affirmative Action/EEO statement:  

Immaticsis an equalopportunityemployer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs.

What do we offer? 

AtImmatics, we believe in investing in our team’s health,safetyand well-being.Here’swhat you can expectif youjoinImmatics:

Comprehensive Benefits: 

• Competitive rates forHealth, Dental, and Vision Insurance

• 4 weeks ofvacation,granted up front each year and prorated for firstand lastyear ofemployment.

• 12 company paid holidays

• 7daysof sick time

• 100%employer-paidlifeinsurance up toat 1x annual salary, up to one hundred thousand dollars

• 100%employer-paidshort- andlong-Termdisabilitycoverage 

• 401(k) withimmediateeligibility andcompany match…

• The company will match100% of your contributions upto3% of yourbase salaryfor the first two yearsof employment, 4% foryears 2-3 of employment, and up to5%of your salaryfrom the fourth year onward of continued employment.

• Partiallypaidparentalleave for eligible employees.

• Additionalvoluntary employee-paidbenefits and services,includingaccident,hospitalindemnity, andcriticalillnessinsurance, as well as identitytheftprotection andpetinsurance.